Evidence map›Paper›PMID 31571256›Full record

ArticleClinical cardiology2019

Cardiovascular risk factors among Ghanaian patients with HIV: A cross-sectional study.

Lambert T Appiah, Fred S Sarfo, Mark D Huffman, Samuel B Nguah, Jonathan K Stiles

Open access · goldAbstract read
In one paragraph

Article in Clinical cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 26 citations in OpenAlex.

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  12. Factors Influencing Survival Status of HIV/AIDS after HAART in Huzhou City, Eastern China.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Lambert T AppiahKomfo Anokye Teaching Hospital, Kumasi, Ghana.ORCID https://orcid.org/0000-0002-8895-2000
Fred S SarfoKomfo Anokye Teaching Hospital, Kumasi, Ghana.
Mark D HuffmanNorthwestern University Feinberg School of Medicine, Chicago, Illinois.
Samuel B NguahKomfo Anokye Teaching Hospital, Kumasi, Ghana.
Jonathan K StilesMorehouse School of Medicine, Atlanta, Georgia.
Komfo Anokye Teaching Hospital · GHMorehouse School of Medicine · USNorthwestern University · US

Funding

UJMT – ORWH – Gazzetta, Issa-BoubeD43TW009340 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI William Checkley, Benjamin H. Chi · 2017 to 2026
$14.8M
6 · The paper itself

Abstract

backgroundCardiovascular disease (CVD) poses a significant cause of morbidity and mortality among people living with human immunodeficiency virus (HIV). However, data are limited on CVD risk burden among HIV patients in Ghana. We describe the age- and sex-adjusted prevalence of CVD risk factors among HIV patients in Ghana.

methodsFrom January 2013 to May 2014, we identified eligible HIV patients 18 years and older, as well as uninfected adult blood donors presenting to the Komfo Anokye Teaching Hospital as controls. Using a standardized protocol, we collected demographic, clinical, laboratory, and electrocardiographic data. We created multivariable logistic regression models to compare the prevalence of abnormal risk factors between the two groups.

resultsWe recruited 345 patients with HIV (n = 173 on HAART, n = 172 not on HAART) and 161 uninfected adult blood donors. Patients with HIV were older (mean [SD] age: 41 [11] vs 32 [11] years) and were more likely to be female (72% vs 28%) than blood donors. Among patients on HAART, median (interquartile range) treatment duration was 17 (4-52) months. The prevalence of hypertension, hypercholesterolemia, and diabetes mellitus among HIV patients was 9%, 29%, and 5%, respectively, compared with 5%, 15%, and 0.6% among uninfected blood donors. Smoking was the least prevalent CVD risk factor (1%-2%). After adjustment for age, sex, and body mass index, HIV patients had a 10-fold higher odds of prevalent diabetes compared with controls, (adjusted OR = 10.3 [95% CI: 1.2, 86.7]).

conclusionCVD risk factors are common among HIV patients in Ghana, demonstrating the urgent need for creation and implementation of strategic CVD interventions.

Indexed as

AdultAntiretroviral Therapy, Highly ActiveCardiovascular DiseasesCross-Sectional StudiesFemaleGhanaHIV InfectionsHumansMaleMiddle AgedPrevalenceRisk FactorsYoung Adultabdominal obesitycardiovascular diseaseCVD riskdiabetes mellitusGhanahigh LDL-Chighly active antiretroviral therapyhypercholesterolemiahypertensionhypertriglyceridemialow HDL-Csmoking

Identifiers

PMID31571256
PMCPMC6906980
OpenAlexW2979176716

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.