Evidence map›Paper›PMID 31571249›Full record

ReviewClinical cardiology2019

Detection of concealed structural heart disease by imaging in patients with apparently idiopathic premature ventricular complexes: A review of current literature.

Biagio Sassone, Daniele Muser, Michela Casella, Mario Luzi, Santo Virzì, Cristina Balla, Gaetano Nucifora, Task Force on Imaging and Task Force on Ablation of Ventricular Tachycardia of the Italian Association of Arrhythmias and Cardiac Pacing (AIAC)

Open access · goldAbstract readReview
In one paragraph

Review in Clinical cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.9field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 20 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Predictors of Myocardial Fibrosis Detected by CMR in Patients With Idiopathic PVCs.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2024
    Article
  5. Article
  6. Abnormal conduction-induced cardiomyopathy: a poorly explored entity.European heart journal supplements : journal of the European Society of Cardiology · 2024
    Article
  7. Idiopathic Annular Ventricular Arrhythmias.Arrhythmia & electrophysiology review · 2024
    Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Recent advances in three-dimensional electroanatomical mapping guidance for the ablation of complex atrial and ventricular arrhythmias.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2021
    Article
  15. Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 4 countries.

Biagio SassoneCardiology Division, SS.ma Annunziata Hospital, Department of Emergency, Azienda Unità Sanitaria Locale di Ferrara, Ferrara, Italy.ORCID https://orcid.org/0000-0002-9028-7169
Daniele MuserCardiothoracic Department, University Hospital, Piazzale Santa Maria della Misericordia 15, Udine, Italy.
Michela CasellaHeart Rhythm Center, Centro Cardiologico Monzino, Milan, Italy.
Mario LuziCardiology Division, Ospedale Provinciale AREA VASTA 3, Macerata MC, Italy.
Santo VirzìCardiology Division, SS.ma Annunziata Hospital, Department of Emergency, Azienda Unità Sanitaria Locale di Ferrara, Ferrara, Italy.
Cristina BallaCardiology Department, S. Anna Hospital, University of Ferrara, Ferrara, Italy.
Gaetano NuciforaCardiology Department, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Wythenshawe, UK.
Task Force on Imaging and Task Force on Ablation of Ventricular Tachycardia of the Italian Association of Arrhythmias and Cardiac Pacing (AIAC)
Azienda Unità Sanitaria Locale di Ferrara · ITCentro Cardiologico Monzino · ITManchester University NHS Foundation Trust · GBOspedale Santa Maria della Misericordia di Udine · ITUniversity of Ferrara · ITUniversity of Macerata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPremature ventricular complexes (PVCs) are the most common form of ventricular arrhythmia in the general population. While in most cases PVCs represent a primitive phenomenon with benign behavior, in a non-negligible proportion of subjects frequent PVCs may be epiphenomenon of underlying occult heart diseases, requiring special medical attention since they have been resulted linked to increased total and cardiac mortality. Nevertheless, PVCs themselves, when incessantly frequent, may be responsible for left ventricular dysfunction in otherwise normal heart. Aim of this narrative review is to update current knowledge on the general approach to patients with frequent PVCs on the basis of available data, with a special focus on the value of imaging. HYPOTHESIS: Routine diagnostic work-up not infrequently miss subtle concealed arrhythmic substrate, leading to erroneously refer to such arrhythmias as to "idiopathic".

methodsLiterature search of PVCs articles was conducted in PubMed and Scopus electronic database.

resultsConflicting data arise from literature about the true clinical significance of idiopathic PVCs. There is growing body of data providing evidence that more advanced non-invasive imaging modalities, such as cardiac magnetic resonance, have an incremental diagnostic and prognostic value. On the other hand, in some cases the prognostic significance of isolated subtle myocardial structural abnormalities in patients with PVCs, still remains area of uncertainty.

conclusionIn selected subjects with PVCs and high-risk features for concealed arrhythmic substrate, traditional assessment to rule out the presence of heart disease, including surface ECG and transthoracic echocardiography, should be implemented with more advanced cardiovascular imaging modalities.

Indexed as

Cardiac Imaging TechniquesHumansVentricular Premature Complexescardiac magnetic resonancepremature ventricular complexesrisk stratification

Identifiers

PMID31571249
PMCPMC6906994
OpenAlexW2978181450

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.