ArticleNature genetics2019
Natural variation in ZmFBL41 confers banded leaf and sheath blight resistance in maize.
Article in Nature genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 115 papers, 1 of them a synthesis that pooled it.
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Who cites it
115 citing papers in PubMed, 1 synthesis or guideline pooled it, 237 citations in OpenAlex.
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- Integrated GWAS and Fst analysis identify flowering-time regulatory genes in maize.The plant genome · 2026Article
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- Allelic Variation in Maize Malate Dehydrogenase 7 Shapes Promoter Methylation and Banded Leaf and Sheath Blight Resistance.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Decades' progress and prospects on maize functional genomics and molecular breeding.Science China. Life sciences · 2025Review
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- Cracking the mysteries of resistance to sheath blight disease: SBRR1 plays a pivotal role.Plant communications · 2025Article
- Comparing hormone dynamics in cereal crops via transient expression of hormone sensors.Plant & cell physiology · 2025Article
- Natural variation in SBRR1 shows high potential for sheath blight resistance breeding in rice.Nature genetics · 2025Article
- SBRR1-R variant regulates sheath blight resistance in rice.Nature genetics · 2025Article
- The OsAP4-OsCATA/OsCATC Regulatory Module Orchestrates Drought Stress Adaptation in Rice Seedlings Through ROS Scavenging.Plants (Basel, Switzerland) · 2025Article
- Fine-mapping of sm6.1, a novel locus conferring resistance to gray leaf spot from Solanum habrochaites accession LA1777.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Mechanism Analysis ofInternational journal of molecular sciences · 2025Article
55 more citing papers are in PubMed but not listed here.
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rhizoctonia solani is a widely distributed phytopathogen that causes banded leaf and sheath blight in maize and sheath blight in rice. Here, we identified an F-box protein (ZmFBL41) that confers resistance to banded leaf and sheath blight through a genome-wide association study in maize. Rice overexpressing ZmFBL41 showed elevated susceptibility to R. solani. Two amino acid substitutions in this allele prevent its interaction with ZmCAD, which encodes the final enzyme in the monolignol biosynthetic pathway, resulting in the inhibition of ZmCAD degradation and, consequently, the accumulation of lignin and restriction of lesion expansion. Knocking out the ZmCAD-homologous gene OsCAD8B in rice enhanced susceptibility to R. solani. The results reveal a susceptibility mechanism in which R. solani targets the host proteasome to modify the secondary metabolism of the plant cell wall for its invasion. More importantly, it provides an opportunity to generate R. solani-resistant varieties of different plant species.
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