Evidence map›Paper›PMID 31570869›Full record

ArticleNature microbiology2019

Identifying residual hotspots and mapping lower respiratory infection morbidity and mortality in African children from 2000 to 2017.

Robert C Reiner, Catherine A Welgan, Daniel C Casey, Christopher E Troeger, Mathew M Baumann, QuynhAnh P Nguyen, Scott J Swartz, Brigette F Blacker, Aniruddha Deshpande, Jonathan F Mosser and 30 more

Registry-linked trialOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05914324 (Evaluating Novel Pediatric Pulse Oximeters for Outpatient Child Pneumonia Care in Sub-Saharan Africa), which is not on this map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05914324 naactive not recruitingnot on this mapstarted 2024, after this paper: background citation

Evaluating Novel Pediatric Pulse Oximeters for Outpatient Child Pneumonia Care in Sub-Saharan Africa

TypeinterventionalSponsorJohns Hopkins UniversityRan2024 to 2026Enrolled936ConditionsChild, Infant, Respiratory Tract Infections, HypoxiaArmsPhefumla device, LB-01 device
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.

  1. Pooled it
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  11. Kitchen fine particulate matter (PMFrontiers in public health · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

40 authors at 5 institutions in 2 countries.

Robert C ReinerInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA. bcreiner@uw.edu.ORCID http://orcid.org/0000-0003-1056-7919
Catherine A WelganInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.
Daniel C CaseyInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.
Christopher E TroegerInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.
Mathew M BaumannInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.
QuynhAnh P NguyenInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.
Scott J SwartzInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.
Brigette F BlackerInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.
Aniruddha DeshpandeInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.
Jonathan F MosserInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.
Aaron E Osgood-ZimmermanInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.
Lucas EarlInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.
Laurie B MarczakInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.
Sandra B MunroInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.
Molly K Miller-PetrieInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.
Grant Rodgers KempInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.
Joseph FrostadInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.
Kirsten E WiensInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.
Paulina A LindstedtInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.
David M PigottInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.
Laura Dwyer-LindgrenInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.
Jennifer M RossDepartment of Global Health, University of Washington, Seattle, WA, USA.
Roy BursteinInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0001-8991-4762
Nicholas GraetzInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.
Puja C RaoInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.
Ibrahim A KhalilInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.
Nicole Davis WeaverInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-7205-9621
Sarah E RayInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.
Ian DavisInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.
Tamer FaragInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.
Oliver J BradyDepartment of Infectious Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, UK.
Moritz U G KraemerDepartment of Zoology, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0001-8838-7147
David L SmithInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0003-4367-3849
Samir BhattImperial College London, London, UK.
Daniel J WeissBig Data Institute, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0002-6175-5648
Peter W GethingBig Data Institute, University of Oxford, Oxford, UK.
Nicholas J KassebaumInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.
Ali H MokdadInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.
Christopher J L MurrayInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.
Simon I HayInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA. sihay@uw.edu.ORCID http://orcid.org/0000-0002-0611-7272
University of Washington · USOpen Data Institute · GBHarvard University · USImperial College London · GBLondon School of Hygiene & Tropical Medicine · GB

Funding

GRADUATE TRAINING IN DEMOGRAPHYT32HD007242 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI MICHEL GUILLOT · 1985 to 2026
$6.6M
Discovery of Novel Natural Products via Characterization of LC/HRMS associated Gene Cluster FamiliesF32GM120999 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI PARKINSON, ELIZABETH IVY · 2017 to 2018
$77k
Medical Research Council MR/R015600/1NICHD NIH HHS T32 HD007242NIGMS NIH HHS F32 GM120999Wellcome Trust 206471/Z/17/Z
6 · The paper itself

Abstract

Lower respiratory infections (LRIs) are the leading cause of death in children under the age of 5, despite the existence of vaccines against many of their aetiologies. Furthermore, more than half of these deaths occur in Africa. Geospatial models can provide highly detailed estimates of trends subnationally, at the level where implementation of health policies has the greatest impact. We used Bayesian geostatistical modelling to estimate LRI incidence, prevalence and mortality in children under 5 subnationally in Africa for 2000-2017, using surveys covering 1.46 million children and 9,215,000 cases of LRI. Our model reveals large within-country variation in both health burden and its change over time. While reductions in childhood morbidity and mortality due to LRI were estimated for almost every country, we expose a cluster of residual high risk across seven countries, which averages 5.5 LRI deaths per 1,000 children per year. The preventable nature of the vast majority of LRI deaths mandates focused health system efforts in specific locations with the highest burden.

Indexed as

MorbidityAfricaBayes TheoremChild, PreschoolHumansIncidenceInfantInfant, NewbornPrevalencePublic HealthRespiratory Tract InfectionsRisk Factors

Identifiers

PMID31570869
PMCPMC6877470
OpenAlexW2976630429

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.