ArticleOncogene2020
Mst1/2 kinases restrain transformation in a novel transgenic model of Ras driven non-small cell lung cancer.
Abstract read
In one paragraph
Article in Oncogene, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 18 citations in OpenAlex.
- EM2, a Natural Product MST1/2 Kinase Activator, Suppresses Non-Small Cell Lung Cancer via Hippo Pathway Activation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- The components and regulation of the Hippo pathway and its relationships with the progression and treatment of Non-small cell lung cancer (NSCLC).Cancer cell international · 2025Review
- Review
- YAP1 facilitates the pathogenesis of psoriasis via modulating keratinocyte proliferation and inflammation.Cell death & disease · 2025Article
- Non-metabolic enzyme function of pyruvate kinase M2 in breast cancer.Frontiers in oncology · 2024Review
- Ginsenoside Rh2 attenuates the progression of non-small cell lung cancer by sponging miR-28-5p/STK4 axis and inactivating Wnt/β-catenin signaling.Cancer medicine · 2023Article
- UM-164, a Dual Inhibitor of c-Src and p38 MAPK, Suppresses Proliferation of Glioma by Reducing YAP Activity.Cancers · 2022Article
- The Hippo pathway in cancer: YAP/TAZ and TEAD as therapeutic targets in cancer.Clinical science (London, England : 1979) · 2022Review
- Kras mutation rate precisely orchestrates ductal derived pancreatic intraepithelial neoplasia and pancreatic cancer.Laboratory investigation; a journal of technical methods and pathology · 2021Article
- The Hippo pathway: an emerging role in urologic cancers.American journal of clinical and experimental urology · 2021Review
- Lung cancer A549 cells suppressed with overexpressed HNF1B or PCDHA13 inhibited PI3K/AKT phosphorylation.Translational cancer research · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 3 institutions in 1 country.
Kanchan Singh *Division of Gastroenterology, Hepatology and Nutrition, Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.
Melissa A Pruski *Division of Gastroenterology, Hepatology and Nutrition, Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.
Kishore PolireddyDivision of Gastroenterology, Hepatology and Nutrition, Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.
Neal C JonesDivision of Gastroenterology, Hepatology and Nutrition, Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.
Qingzheng ChenDivision of Gastroenterology, Hepatology and Nutrition, Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.
Jun YaoDepartment of Molecular and Cellular Oncology, The University of Texas MDAnderson Cancer Center, Houston, TX, 77030, USA.
Wasim A DarDivision of Immunology and Organ Transplantation, Department of Surgery, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.
Florencia McAllisterDepartment of Clinical Cancer Prevention, The University of Texas MDAnderson Cancer Center, Houston, TX, 77030, USA.
Cynthia JuDepartment of Anesthesiology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.
Holger K EltzschigDepartment of Anesthesiology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.
Mamoun YounesDepartment of Pathology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.ORCID http://orcid.org/0000-0001-9618-3451
Cesar MoranDepartment of Pathology, The University of Texas MDAnderson Cancer Center, Houston, TX, 77030, USA.
Harry Karmouty-QuintanaDepartment of Biochemistry, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.
Haoqiang YingDepartment of Molecular and Cellular Oncology, The University of Texas MDAnderson Cancer Center, Houston, TX, 77030, USA.
Jennifer M BaileyDivision of Gastroenterology, Hepatology and Nutrition, Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA. Jennifer.M.Bailey@uth.tmc.edu.
The University of Texas Health Science Center at Houston · USThe University of Texas MD Anderson Cancer Center · USThe University of Texas Health Science Center · US
Funding
Trangenic Mouse Breeding CoreP01HL114457 · NHLBI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI ZHANG, YUJIN · 2013 to 2017
$10.0MNovel Immunologic Effects of Semaphorin 7a in IPFR01HL109233 · NHLBI · YALE UNIVERSITY · PI HERZOG, ERICA L · 2011 to 2019
$3.7MSHORT TERM RESEARCH TRAININGT35DK007676 · NIDDK · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI KONE, BRUCE C. · 1992 to 2017
$1.8MHypoxia-Inducible Factors in Acetaminophen-Induced Liver Injury.R01DK109574 · NIDDK · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI ELTZSCHIG, HOLGER K., JU, CYNTHIA · 2016 to 2019
$1.8MProton Pump Inhibitors for Perioperative Acute Kidney InjuryR01DK097075 · NIDDK · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI ELTZSCHIG, HOLGER K. · 2013 to 2017
$1.7MAmphiregulin Signaling in Perioperative Cardio-ProtectionR01HL119837 · NHLBI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI ELTZSCHIG, HOLGER K. · 2014 to 2017
$1.5MMicroRNA Shuttling during Acute Respiratory Distress SyndromeR01HL133900 · NHLBI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI ELTZSCHIG, HOLGER K. · 2017 to 2020
$1.5MNHLBI NIH HHS P01 HL114457NHLBI NIH HHS R01 HL109233NHLBI NIH HHS R01 HL119837NHLBI NIH HHS R01 HL133900NIDDK NIH HHS R01 DK097075NIDDK NIH HHS R01 DK109574NIDDK NIH HHS T35 DK007676
Abstract
Non-small cell lung cancer remains a highly lethal malignancy. Using the tamoxifen inducible Hnf1b:CreER
Indexed as
Cell Transformation, NeoplasticDisease Models, AnimalAnimalsCarcinoma, Non-Small-Cell LungCarrier ProteinsCell Line, TumorGene DeletionHepatocyte Nuclear Factor 1-betaHippo KinasesIntracellular Signaling Peptides and ProteinsLungLung NeoplasmsMembrane ProteinsMiceMice, TransgenicProtein Serine-Threonine KinasesCarrier ProteinsHepatocyte Nuclear Factor 1-betaHippo KinasesHNF1B protein, humanIntracellular Signaling Peptides and ProteinsMembrane ProteinsProtein Serine-Threonine Kinasesras ProteinsSerine-Threonine Kinase 3STK3 protein, humanSTK4 protein, humanThyroid Hormone-Binding ProteinsThyroid Hormones
Identifiers
What OpenQuestion holds
Textmetadata
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.