ArticleScientific reports2019
Transcriptomic comparison between beetle strains selected for short and long durations of death feigning.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9 citing papers in PubMed, 30 citations in OpenAlex.
- Tribolium castaneum with longer duration of tonic immobility have more variations corresponding to the human Parkinson's disease genomic region.Scientific reports · 2026Article
- Behavior, behavioral syndromes, and metabolism: the effects of artificial selection for death-feigning on metabolic rate.Journal of insect science (Online) · 2025Article
- Transcriptomic comparison between populations selected for higher and lower mobility in the red flour beetle Tribolium castaneum.Scientific reports · 2024Article
- Why fake death? Environmental and genetic control of tonic immobility in larval lacewings (Neuroptera: Chrysopidae).Journal of insect science (Online) · 2023Article
- Freezing or death feigning? Beetles selected for long death feigning showed different tactics against different predators.Ecology and evolution · 2022Article
- Genomic characterization between strains selected for death-feigning duration for avoiding attack of a beetle.Scientific reports · 2021Article
- Cross-species behavior analysis with attention-based domain-adversarial deep neural networks.Nature communications · 2021Article
- Tonic Immobility Is Influenced by Starvation, Life Stage, and Body Mass in Ixodid Ticks.Journal of medical entomology · 2021Article
- Synchronising anti-predator behavior in the red flour beetleBehavioral ecology : official journal of the International Society for Behavioral EcologyArticle
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The molecular basis of death feigning, an antipredator behavior that has received much attention recently, was analyzed. We compared the gene expression profiles of strains with different behaviors, i.e., different durations of death feigning, in the beetle Tribolium castaneum. Beetles artificially selected for short (S) and long (L) durations of death feigning for many generations were compared thoroughly by RNA sequencing. We identified 518 differentially expressed genes (DEGs) between the strains. The strains also showed divergence in unexpected gene expression regions. As expected from previous physiological studies, genes associated with the metabolic pathways of tyrosine, a precursor of dopamine, were differentially expressed between the S and L strains; these enzyme-encoding genes were expressed at higher levels in the L strain than in the S strain. We also found that several genes associated with insulin signaling were expressed at higher levels in the S strain than in the L strain. Quantitative real-time PCR analysis showed that the relative expression levels of Tchpd (encoding 4-hydroxyphenylpyruvate dioxygenase, Hpd) and Tcnat (encoding N-acetyltransferase, Nat) were significantly higher in the L strain than in the S strain, suggesting the influence of these enzymes on the supply of dopamine and duration of death feigning.
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