ArticleNature communications2019
Neurogenomic insights into paternal care and its relation to territorial aggression.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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Who cites it
27 citing papers in PubMed, 46 citations in OpenAlex.
- Prolactin-PRLR-STAT5 signaling upregulates a candidate pheromone receptor caor67 in the olfactory epithelium of northern snakehead (Channa argus).Fish physiology and biochemistry · 2026Article
- Paternal behavior is controlled by preoptic Trpc5 neurons.bioRxiv : the preprint server for biology · 2026Article
- Sex and breeding stage differences in neurogenomic profiles reflect hormone signaling in a socially polyandrous shorebird.bioRxiv : the preprint server for biology · 2026Article
- Predator Communities With Invasive Pike Are Associated With Changes in Parental Care and Brain Gene Expression in Wild Alaskan Stickleback.Integrative and comparative biology · 2026Article
- Building neuroanatomical resources for three-spined sticklebacks: Brain areas important for social behavior.bioRxiv : the preprint server for biology · 2026Article
- A holistic review of fatherhood in humans and non-human animals: mechanisms of fatherhood, effects on fathers themselves, and interactions of fathers with others.Frontiers in behavioral neuroscience · 2026Review
- Male caregiving experience alters hippocampal neuroplasticity and transcription independent of reproduction in a biparental species.Communications biology · 2025Article
- Single-Cell Peptide Profiling to Distinguish Stickleback Ecotypes with Divergent Breeding Behavior.Journal of proteome research · 2025Article
- QTL-Based Evidence of Population Genetic Divergence in Male Territorial Aggressiveness of the Japanese Freshwater Threespine Stickleback.Ecology and evolution · 2025Article
- An Evolutionary Loss of Parental Care in Stickleback Is Associated with Differences in the Activity, but Not the Number, of Neuropeptidergic Neurons in the Preoptic Area.Brain, behavior and evolution · 2025Article
- The neurobiology of parenting and infant-evoked aggression.Physiological reviews · 2025Review
- Managing the tradeoff between reproduction and survival requires flexibility in behaviour and gene regulation in three-spined stickleback.Proceedings. Biological sciences · 2024Article
- Oxytocin influences parental care in male threespine stickleback across multiple time scales.Hormones and behavior · 2024Article
- Environmental enrichment attenuates depressive-like behavior in maternal rats by inhibiting neuroinflammation and apoptosis and promoting neuroplasticity.Neurobiology of stress · 2024Article
- The evolution of decision-making mechanisms under competing demands.Trends in ecology & evolution · 2024Review
- A distinct neurogenomic response to a trade-off between social challenge and opportunity in male sticklebacks (Biology letters · 2023Article
- Transcriptomic changes associated with maternal care in the brain of mouthbrooding cichlid Astatotilapia burtoni reflect adaptation to self-induced metabolic stress.The Journal of experimental biology · 2023Article
- An accessory prefrontal cortex-thalamus circuit sculpts maternal behavior in virgin female mice.The EMBO journal · 2022Article
- Insights into Parental Care from Studies on Non-mammalian Vertebrates.Affective science · 2022Article
- Whole-brain optical access in a small adult vertebrate with two- and three-photon microscopy.iScience · 2022Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Motherhood is characterized by dramatic changes in brain and behavior, but less is known about fatherhood. Here we report that male sticklebacks-a small fish in which fathers provide care-experience dramatic changes in neurogenomic state as they become fathers. Some genes are unique to different stages of paternal care, some genes are shared across stages, and some genes are added to the previously acquired neurogenomic state. Comparative genomic analysis suggests that some of these neurogenomic dynamics resemble changes associated with pregnancy and reproduction in mammalian mothers. Moreover, gene regulatory analysis identifies transcription factors that are regulated in opposite directions in response to a territorial challenge versus during paternal care. Altogether these results show that some of the molecular mechanisms of parental care might be deeply conserved and might not be sex-specific, and suggest that tradeoffs between opposing social behaviors are managed at the gene regulatory level.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.