ArticleProceedings of the National Academy of Sciences of the United States of America2019
Noncanonical auxin signaling regulates cell division pattern during lateral root development.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.
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Who cites it
58 citing papers in PubMed.
- Lateral Root Development: Molecular Mechanisms and Adaptive Regulation.Plant, cell & environment · 2026Review
- MPK3 as a Signalling Hub in Plants: Integrating Plant Growth, Development and Stress Response.Plants (Basel, Switzerland) · 2026Article
- Transcriptome profiling reveals divergent response strategies in two olive cultivars with contrasting drought tolerance.Plant physiology · 2026Article
- Auxin Biosynthesis, Transport, Signaling, and Its Roles in Plant Leaf Morphogenesis.Plants (Basel, Switzerland) · 2025Review
- Mechanisms of auxin action in plant growth and development.Nature reviews. Molecular cell biology · 2025Review
- Jack of all trades: crosstalk between FERONIA signaling and hormone pathways.Journal of experimental botany · 2025Review
- Mitogen-Activated Protein Kinases 3/6 Reduce Auxin Signaling via Stabilizing Indoleacetic Acid-Induced Proteins 8/9 in Plant Abiotic Stress Adaptation.International journal of molecular sciences · 2025Article
- Spatial Distribution Characteristics of Micronutrients and Their Deficiency Effect on the Root Morphology and Architecture in Citrus Rootstock.Plants (Basel, Switzerland) · 2025Article
- Historical and mechanistic perspective on ABP1-TMK1-mediated cell surface auxin signaling.NPJ science of plants · 2025Review
- Molecular traits of MAPK kinases and the regulatory mechanism of GhMAPKK5 alleviating drought/salt stress in cotton.Plant physiology · 2024Article
- Research on the Mechanisms of Phytohormone Signaling in Regulating Root Development.Plants (Basel, Switzerland) · 2024Review
- Shaping root architecture: towards understanding the mechanisms involved in lateral root development.Biology direct · 2024Review
- Slow and rapid auxin responses in Arabidopsis.Journal of experimental botany · 2024Article
- A gain-of-function mutation in BnaIAA13 disrupts vascular tissue and lateral root development in Brassica napus.Journal of experimental botany · 2024Article
- MAC3A and MAC3B mediate degradation of the transcription factor ERF13 and thus promote lateral root emergence.The Plant cell · 2024Article
- Nitrate Starvation Induces Lateral Root Organogenesis inInternational journal of molecular sciences · 2024Article
- VIK-Mediated Auxin Signaling Regulates Lateral Root Development in Arabidopsis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Hierarchical global and local auxin signals coordinate cellular interdigitation inbioRxiv : the preprint server for biology · 2024Article
- Root branching under high salinity requires auxin-independent modulation of LATERAL ORGAN BOUNDARY DOMAIN 16 function.The Plant cell · 2024Article
- AtIAR1 is a Zn transporter that regulates auxin metabolism in Arabidopsis thaliana.Journal of experimental botany · 2024Article
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7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
In both plants and animals, multiple cellular processes must be orchestrated to ensure proper organogenesis. The cell division patterns control the shape of growing organs, yet how they are precisely determined and coordinated is poorly understood. In plants, the distribution of the phytohormone auxin is tightly linked to organogenesis, including lateral root (LR) development. Nevertheless, how auxin regulates cell division pattern during lateral root development remains elusive. Here, we report that auxin activates Mitogen-Activated Protein Kinase (MAPK) signaling via transmembrane kinases (TMKs) to control cell division pattern during lateral root development. Both TMK1/4 and MKK4/5-MPK3/6 pathways are required to properly orient cell divisions, which ultimately determine lateral root development in response to auxin. We show that TMKs directly and specifically interact with and phosphorylate MKK4/5, which is required for auxin to activate MKK4/5-MPK3/6 signaling. Our data suggest that TMK-mediated noncanonical auxin signaling is required to regulate cell division pattern and connect auxin signaling to MAPK signaling, which are both essential for plant development.
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