Evidence map›Paper›PMID 31570595›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Extrapituitary prolactin promotes generation of Eomes-positive helper T cells mediating neuroinflammation.

Chenyang Zhang, Ben J E Raveney, Hirohiko Hohjoh, Chiharu Tomi, Shinji Oki, Takashi Yamamura

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. A prolactin-targeting antibody to prevent stress-induced peripheral nociceptor sensitization and female postoperative pain.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Article
  5. Terminally differentiated cytotoxic CD4CNS neuroscience & therapeutics · 2024
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Involvement of cytotoxic Eomes-expressing CD4Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Chenyang ZhangDepartment of Immunology, National Institute of Neuroscience, Tokyo 187-0031, Japan.ORCID 0000-0001-9910-3533
Ben J E RaveneyDepartment of Immunology, National Institute of Neuroscience, Tokyo 187-0031, Japan.
Hirohiko HohjohDepartment of Molecular Pharmacology, National Institute of Neuroscience, Tokyo 187-8502, Japan.
Chiharu TomiDepartment of Immunology, National Institute of Neuroscience, Tokyo 187-0031, Japan.
Shinji OkiDepartment of Immunology, National Institute of Neuroscience, Tokyo 187-0031, Japan; soki@ncnp.go.jp yamamura@ncnp.go.jp.
Takashi YamamuraDepartment of Immunology, National Institute of Neuroscience, Tokyo 187-0031, Japan; soki@ncnp.go.jp yamamura@ncnp.go.jp.
National Center of Neurology and Psychiatry · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Induction of eomesodermin-positive CD4

Indexed as

AnimalsB-LymphocytesCD4-Positive T-LymphocytesCentral Nervous SystemDisease Models, AnimalEncephalomyelitis, Autoimmune, ExperimentalInflammationMiceMice, Inbred C57BLMultiple SclerosisMyeloid CellsProlactinT-Box Domain ProteinsEomes protein, mouseProlactinT-Box Domain Proteinsantigen-presenting cellexperimental autoimmune encephalomyelitismultiple sclerosisprolactin

Identifiers

PMID31570595
PMCPMC6800326
OpenAlexW2977830896

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.