Evidence map›Paper›PMID 31570562›Full record

ArticleInfection and immunity2019

Particles from the Echinococcus granulosus Laminated Layer Inhibit CD40 Upregulation in Dendritic Cells by Interfering with Akt Activation.

Álvaro Pittini, Yamila E Martínez-Acosta, Cecilia Casaravilla, Paula I Seoane, Dominik Rückerl, Celia Quijano, Judith E Allen, Álvaro Díaz

Open access · hybridAbstract read
In one paragraph

Article in Infection and immunity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
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  5. First In Silico Study of TwoInternational journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Álvaro PittiniÁrea Inmunología, Departamento de Biociencias (Facultad de Química) and Cátedra de Inmunología, Instituto de Química Biológica (Facultad de Ciencias), Universidad de la República, Montevideo, Uruguay.
Yamila E Martínez-AcostaÁrea Inmunología, Departamento de Biociencias (Facultad de Química) and Cátedra de Inmunología, Instituto de Química Biológica (Facultad de Ciencias), Universidad de la República, Montevideo, Uruguay.
Cecilia CasaravillaÁrea Inmunología, Departamento de Biociencias (Facultad de Química) and Cátedra de Inmunología, Instituto de Química Biológica (Facultad de Ciencias), Universidad de la República, Montevideo, Uruguay.
Paula I SeoaneÁrea Inmunología, Departamento de Biociencias (Facultad de Química) and Cátedra de Inmunología, Instituto de Química Biológica (Facultad de Ciencias), Universidad de la República, Montevideo, Uruguay.
Dominik RückerlLydia Becker Institute for Immunology and Inflammation, Faculty of Biology, Medicine, and Health, School of Biological Sciences, University of Manchester, Manchester, United Kingdom.
Celia QuijanoCenter for Free Radical and Biomedical Research (CEINBIO) and Departamento de Bioquímica (Facultad de Medicina), Universidad de la República, Montevideo, Uruguay.
Judith E AllenLydia Becker Institute for Immunology and Inflammation, Faculty of Biology, Medicine, and Health, School of Biological Sciences, University of Manchester, Manchester, United Kingdom.
Álvaro DíazÁrea Inmunología, Departamento de Biociencias (Facultad de Química) and Cátedra de Inmunología, Instituto de Química Biológica (Facultad de Ciencias), Universidad de la República, Montevideo, Uruguay adiaz@fq.edu.uy.ORCID 0000-0001-5375-6766
Universidad de la República de Uruguay · UYUniversity of Manchester · GB

Funding

Wellcome TrustWellcome Trust 092752/Z/10/Z
6 · The paper itself

Abstract

The larval stage of the cestode

Indexed as

AnimalsCD40 AntigensCells, CulturedDendritic CellsEchinococcosisEchinococcus granulosusEnzyme ActivationGlycogen Synthase Kinase 3Granulocyte-Macrophage Colony-Stimulating FactorInterleukin-4LipopolysaccharidesMiceMice, Inbred C57BLPhagocytosisPhosphatidylinositol 3-KinasesPhosphorylationCD40 AntigensGlycogen Synthase Kinase 3Granulocyte-Macrophage Colony-Stimulating FactorIl4 protein, mouseInterleukin-4LipopolysaccharidesPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktAKT signalingCD40dendritic cellsEchinococcushelminthsmembrane affinity-triggered signalingPI3K

Identifiers

PMID31570562
PMCPMC6867849
OpenAlexW2977373424

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.