Evidence map›Paper›PMID 31570521›Full record

ArticleThe Journal of biological chemistry2019

Nucleic acid-induced dimerization of HIV-1 Gag protein.

Huaying Zhao, Siddhartha A K Datta, Sung H Kim, Samuel C To, Sumit K Chaturvedi, Alan Rein, Peter Schuck

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Embedding of HIV Egress within Cortical F-Actin.Pathogens (Basel, Switzerland) · 2022
    Article
  9. Review
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Huaying ZhaoDynamics of Macromolecular Assembly Section, Laboratory of Cellular Imaging and Macromolecular Biophysics, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland 20892.ORCID 0000-0002-8827-6639
Siddhartha A K DattaHIV Dynamics and Replication Program, Center for Cancer Research, NCI, National Institutes of Health, Frederick, Maryland 21702.
Sung H KimDynamics of Macromolecular Assembly Section, Laboratory of Cellular Imaging and Macromolecular Biophysics, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland 20892.
Samuel C ToDynamics of Macromolecular Assembly Section, Laboratory of Cellular Imaging and Macromolecular Biophysics, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland 20892.
Sumit K ChaturvediDynamics of Macromolecular Assembly Section, Laboratory of Cellular Imaging and Macromolecular Biophysics, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland 20892.
Alan ReinHIV Dynamics and Replication Program, Center for Cancer Research, NCI, National Institutes of Health, Frederick, Maryland 21702.ORCID 0000-0002-8273-546X
Peter SchuckDynamics of Macromolecular Assembly Section, Laboratory of Cellular Imaging and Macromolecular Biophysics, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland 20892 peter.schuck@nih.gov.ORCID 0000-0002-8859-6966
National Institutes of Health · USNational Institute of Biomedical Imaging and Bioengineering · US

Funding

Dynamics of Protein Assemblies by Analytical UltracentrifugationZIAEB000051 · NIBIB · NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING · PI SCHUCK, PETER · 2009 to 2025
$7.9M
Interactions of Retroviral Proteins with Nucleic AcidsZIABC010512 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI REIN, ALAN · 2009 to 2025
$7.7M
Intramural NIH HHS ZIA BC010512Intramural NIH HHS ZIA EB000051
6 · The paper itself

Abstract

HIV-1 Gag is a highly flexible multidomain protein that forms the protein lattice of the immature HIV-1 virion.

Indexed as

CalorimetryDimerizationgag Gene Products, Human Immunodeficiency VirusHIV-1HumansKineticsOligonucleotidesProtein BindingProtein DomainsSpectrometry, FluorescenceThermodynamicsgag Gene Products, Human Immunodeficiency VirusOligonucleotidesanalytical ultracentrifugationfluorescencefluorescence-detected sedimentation velocityGag multimerizationhuman immunodeficiency virus (HIV)protein-nucleic acid interactionprotein oligomerizationvirus assemblyvirus-like particle (VLP)

Identifiers

PMID31570521
PMCPMC6851336
OpenAlexW2977477797

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.