Evidence map›Paper›PMID 31570231›Full record

ArticleBiophysical journal2019

Effect of Post-Translational Modifications and Mutations on Amyloid-β Fibrils Dynamics at N Terminus.

Liliya Vugmeyster, Dan F Au, Dmitry Ostrovsky, Brian Kierl, Riqiang Fu, Zhi-Wen Hu, Wei Qiang

Open access · bronzeAbstract read
In one paragraph

Article in Biophysical journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Effect of Cross-Seeding of Wild-Type Amyloid-βThe journal of physical chemistry. B · 2023
    Article
  6. Review
  7. Review
  8. Deuteron rotating frame relaxation for the detection of slow motions in rotating solids.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2022
    Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Liliya VugmeysterDepartment of Chemistry, University of Colorado Denver, Denver, Colorado. Electronic address: liliya.vugmeyster@ucdenver.edu.
Dan F AuDepartment of Chemistry, University of Colorado Denver, Denver, Colorado.
Dmitry OstrovskyDepartment of Mathematics, University of Colorado Denver, Denver, Colorado.
Brian KierlDepartment of Chemistry, University of Colorado Denver, Denver, Colorado.
Riqiang FuNational High Field Magnetic Laboratory, Tallahassee, Florida.
Zhi-Wen HuDepartment of Chemistry, Binghamton University, Binghamton, New York.
Wei QiangDepartment of Chemistry, Binghamton University, Binghamton, New York.
University of Colorado Denver · USBinghamton University · USNational High Magnetic Field Laboratory · US

Funding

Molecular Structural Basis of Non-specific Neuronal Membrane Disruption Induced by Early-Stage Beta-Amyloid Peptide AggregationR01GM125853 · NIGMS · STATE UNIVERSITY OF NY,BINGHAMTON · PI Wei Qiang · 2018 to 2026
$2.5M
Variant-specific dynamics of amyloid-b fibrilsR15GM111681 · NIGMS · UNIVERSITY OF COLORADO DENVER · PI VUGMEYSTER, LILIYA · 2014 to 2021
$1.3M
NIGMS NIH HHS R01 GM125853NIGMS NIH HHS R15 GM111681
6 · The paper itself

Abstract

We investigate the variability in the dynamics of the disordered N-terminal domain of amyloid-β fibrils (Aβ), comprising residues 1-16 of Aβ

Indexed as

MutationProtein Processing, Post-TranslationalAmyloid beta-PeptidesMolecular Dynamics SimulationPhosphorylationProtein DomainsProtein MultimerizationZincAmyloid beta-PeptidesZinc

Identifiers

PMID31570231
PMCPMC6817547
OpenAlexW2972501423

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.