Evidence map›Paper›PMID 31570117›Full record

ArticleeLife2019

Functional brain alterations following mild-to-moderate sensorineural hearing loss in children.

Axelle Calcus, Outi Tuomainen, Ana Campos, Stuart Rosen, Lorna F Halliday

Abstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Axelle CalcusLaboratoire des Systèmes Perceptifs, Département d'Etudes Cognitives, Ecole Normale Supérieure, PSL University, CNRS, Paris, France.ORCID 0000-0002-1240-1122
Outi TuomainenDepartment of Speech, Hearing and Phonetic Sciences, University College London, London, United Kingdom.
Ana CamposDepartment of Speech, Hearing and Phonetic Sciences, University College London, London, United Kingdom.
Stuart RosenDepartment of Speech, Hearing and Phonetic Sciences, University College London, London, United Kingdom.
Lorna F HallidayDepartment of Speech, Hearing and Phonetic Sciences, University College London, London, United Kingdom.ORCID 0000-0003-1883-7741

Funding

ESRC RES-061-25-0440ESRC National Centre for Research Methods, University of Southampton RES-061-25-0440H2020 Marie Skłodowska-Curie Actions FP7-607139
6 · The paper itself

Abstract

Auditory deprivation in the form of deafness during development leads to lasting changes in central auditory system function. However, less is known about the effects of mild-to-moderate sensorineural hearing loss (MMHL) during development. Here, we used a longitudinal design to examine late auditory evoked responses and mismatch responses to nonspeech and speech sounds for children with MMHL. At Time 1, younger children with MMHL (8-12 years; n = 23) showed age-appropriate mismatch negativities (MMNs) to sounds, but older children (12-16 years; n = 23) did not. Six years later, we re-tested a subset of the younger (now older) children with MMHL (n = 13). Children who had shown significant MMNs at Time 1 showed MMNs that were reduced and, for nonspeech, absent at Time 2. Our findings demonstrate that even a mild-to-moderate hearing loss during early-to-mid childhood can lead to changes in the neural processing of sounds in late childhood/adolescence.

Indexed as

Auditory PerceptionAdolescentBrain DiseasesChildChild DevelopmentChild, PreschoolEvoked Potentials, AuditoryFemaleHearing Loss, SensorineuralHumansInfantLongitudinal StudiesMaleauditorydevelopmenthearing losshumanLAERMMNneuroscience

Identifiers

PMID31570117
PMCPMC6828531

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.