Evidence map›Paper›PMID 31570096›Full record

Trial reportJournal of translational medicine2019

Predictive model for acute respiratory distress syndrome events in ICU patients in China using machine learning algorithms: a secondary analysis of a cohort study.

Xian-Fei Ding, Jin-Bo Li, Huo-Yan Liang, Zong-Yu Wang, Ting-Ting Jiao, Zhuang Liu, Liang Yi, Wei-Shuai Bian, Shu-Peng Wang, Xi Zhu and 1 more

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in Journal of translational medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07328997 (Exploration of Diagnosis and Treatment Strategies and Prognostic Prediction Models for Acute Respiratory Distress Syndrome Based on Radiographic Evaluations Assessed by Artificial Intelligence), which is not on this map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07328997 completednot on this mapstarted 2024, after this paper: background citation

Exploration of Diagnosis and Treatment Strategies and Prognostic Prediction Models for Acute Respiratory Distress Syndrome Based on Radiographic Evaluations Assessed by Artificial Intelligence

TypeobservationalSponsorShanghai Zhongshan HospitalRan2024 to 2025Enrolled400ConditionsARDS (Acute Respiratory Distress Syndrome), AI (Artificial Intelligence)ArmsCT scan
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xian-Fei DingDepartment of General ICU, The First Affiliated Hospital of Zhengzhou University, Henan Key Laboratory of Critical Care Medicine, 1 Jianshe East Road, Zhengzhou, 450052, China.
Jin-Bo LiDepartment of General ICU, The First Affiliated Hospital of Zhengzhou University, Henan Key Laboratory of Critical Care Medicine, 1 Jianshe East Road, Zhengzhou, 450052, China.
Huo-Yan LiangDepartment of General ICU, The First Affiliated Hospital of Zhengzhou University, Henan Key Laboratory of Critical Care Medicine, 1 Jianshe East Road, Zhengzhou, 450052, China.
Zong-Yu WangDepartment of Critical Care Medicine, Peking University Third Hospital, Beijing, China.
Ting-Ting JiaoDepartment of General ICU, The First Affiliated Hospital of Zhengzhou University, Henan Key Laboratory of Critical Care Medicine, 1 Jianshe East Road, Zhengzhou, 450052, China.
Zhuang LiuIntensive Care Unit, Beijing Friendship Hospital Affiliated with Capital Medical University, Beijing, China.
Liang YiIntensive Care Unit, Xiyuan Hospital Affiliated with the China Academy of Chinese Medical Sciences, Beijing, China.
Wei-Shuai BianIntensive Care Unit, Beijing Shijitan Hospital Affiliated with Capital Medical University, Beijing, China.
Shu-Peng WangIntensive Care Unit, China-Japan Friendship Hospital, Beijing, China.
Xi ZhuDepartment of Critical Care Medicine, Peking University Third Hospital, Beijing, China. xizhuccm@163.com.
Tong-Wen SunDepartment of General ICU, The First Affiliated Hospital of Zhengzhou University, Henan Key Laboratory of Critical Care Medicine, 1 Jianshe East Road, Zhengzhou, 450052, China. suntongwen@163.com.ORCID 0000-0001-6536-3222

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo develop a machine learning model for predicting acute respiratory distress syndrome (ARDS) events through commonly available parameters, including baseline characteristics and clinical and laboratory parameters.

methodsA secondary analysis of a multi-centre prospective observational cohort study from five hospitals in Beijing, China, was conducted from January 1, 2011, to August 31, 2014. A total of 296 patients at risk for developing ARDS admitted to medical intensive care units (ICUs) were included. We applied a random forest approach to identify the best set of predictors out of 42 variables measured on day 1 of admission.

resultsAll patients were randomly divided into training (80%) and testing (20%) sets. Additionally, these patients were followed daily and assessed according to the Berlin definition. The model obtained an average area under the receiver operating characteristic (ROC) curve (AUC) of 0.82 and yielded a predictive accuracy of 83%. For the first time, four new biomarkers were included in the model: decreased minimum haematocrit, glucose, and sodium and increased minimum white blood cell (WBC) count.

conclusionsThis newly established machine learning-based model shows good predictive ability in Chinese patients with ARDS. External validation studies are necessary to confirm the generalisability of our approach across populations and treatment practices.

Indexed as

AlgorithmsIntensive Care UnitsMachine LearningModels, TheoreticalAgedChinaCohort StudiesFemaleHumansMaleMiddle AgedRespiratory Distress SyndromeROC CurveAcute respiratory distress syndromeMachine learningPredictive model

Identifiers

PMID31570096
PMCPMC6771100

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.