Evidence map›Paper›PMID 31569814›Full record

ArticleMicromachines2019

Microfluidic Passive Flow Regulatory Device with an Integrated Check Valve for Enhanced Flow Control.

Xinjie Zhang, Zhenyu Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Micromachines, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Xinjie ZhangCollege of Mechanical and Electrical Engineering, Hohai University, Changzhou 213022, China. xj.zhang@hhu.edu.cn.
Zhenyu ZhangCollege of Mechanical and Electrical Engineering, Hohai University, Changzhou 213022, China.

Funding

China Postdoctoral Science Foundation 2019M651643National Natural Science Foundation of China 51905150Natural Science Foundation of Jiangsu Province BK20180419
6 · The paper itself

Abstract

A passive microvalve has appealing advantages in cost-effective and miniaturized microfluidic applications. In this work, we present a passive flow regulatory device for enhanced flow control in a microfluidic environment. The device was integrated with two functional elements, including a flow regulating valve and a flow check valve. Importantly, the flow regulating valve could maintain a stable flow rate over a threshold liquid pressure, and the flow check valve enabled effective liquid on/off control, thus accurate forward flow without any backward leakage was achieved. The flow performance of the flow regulating valve was analyzed through 3D FSI (Fluid-Structure Interaction) simulation, and several key parameters (i.e., fluidic channel height and width, control channel length, and Young's modulus) were found to influence valve flow rate directly. To examine the flow characteristics of the device, we fabricated a prototype using 3D printing and UV laser cutting technologies, and the flow rates of the prototype under varied test pressures were measured in forward and reverse modes, respectively. Experimental results showed that nearly a constant flow rate of 0.42 ± 0.02 mL s

Indexed as

flow autoregulationflow check valveflow regulating valvemicrofluidic

Identifiers

PMID31569814
PMCPMC6843763

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.