Evidence map›Paper›PMID 31569686›Full record

ArticleBiomolecules2019

Discovery of Serotransferrin Glycoforms: Novel Markers for Diagnosis of Liver Periductal Fibrosis and Prediction of Cholangiocarcinoma.

Wassana Jamnongkan, Carlito B Lebrilla, Mariana Barboza, Anchalee Techasen, Watcharin Loilome, Paiboon Sithithaworn, Narong Khuntikeo, Chawalit Pairojkul, Nittaya Chamadol, Raynoo Thanan and 1 more

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

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  9. ACS omega · 2022
    Article
  10. Article
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  12. Application ofInternational journal of molecular sciences · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Wassana JamnongkanDepartment of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand. wassana_jk@hotmail.co.th.
Carlito B LebrillaDepartment of Chemistry, University of California, Davis, CA 95616, USA. cblebrilla@ucdavis.edu.
Mariana BarbozaDepartment of Chemistry, University of California, Davis, CA 95616, USA. mbarboza@ucdavis.edu.
Anchalee TechasenCholangiocarcinoma Research Institute, Khon Kaen University, Khon Kaen 40002, Thailand. anchte@kku.ac.th.
Watcharin LoilomeDepartment of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand. watclo@kku.ac.th.ORCID 0000-0001-8572-5577
Paiboon SithithawornDepartment of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand. paib_sit@kku.ac.th.
Narong KhuntikeoCholangiocarcinoma Research Institute, Khon Kaen University, Khon Kaen 40002, Thailand. nkhuntikeo@gmail.com.
Chawalit PairojkulDepartment of Pathology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand. chawalit-pjk2011@hotmail.com.
Nittaya ChamadolDepartment of Radiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand. nittayachamadol@yahoo.com.
Raynoo ThananDepartment of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand. raynoo@kku.ac.th.ORCID 0000-0002-9001-1197
Puangrat YongvanitDepartment of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand. puangrat@kku.ac.th.
Khon Kaen University · THUniversity of California, Davis · USUniversity of California System · US

Funding

The incorporation of human milk oligosaccharides in brain glycoconjugatesR01GM049077 · NIGMS · UNIVERSITY OF CALIFORNIA DAVIS · PI LEBRILLA, CARLITO B · 1999 to 2024
$6.3M
NIGMS NIH HHS R01 GM049077
6 · The paper itself

Abstract

Cholangiocarcinoma (CCA) caused by chronic liver fluke infection is a major public health problem in Northeast Thailand. Identification of CCA risk groups is urgently needed for the control of CCA in this region. Periductal fibrosis (PDF) induced by chronic inflammation of bile ducts is known as a pre-neoplastic lesion of CCA. We aimed to identify the serum CCA and PDF biomarkers using mass spectrometry (UPLC-ESI-QqQ) with multiple reaction mode (MRM) analysis. Here, serum levels of serotransferrin glycoforms at the glycopeptide level were measured in the sera of CCA (

Indexed as

Biomarkers, TumorCholangiocarcinomaFemaleHumansLiver CirrhosisMaleMiddle AgedROC CurveTransferrinBiomarkers, TumorTransferrinbiomarkerscholangiocarcinomaglycobiologyliver flukemass spectrometryperiductal fibrosisserotransferrin

Identifiers

PMID31569686
PMCPMC6843847
OpenAlexW2976186472

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.