Evidence map›Paper›PMID 31569559›Full record

ReviewCancers2019

Replication Stress Response Links RAD52 to Protecting Common Fragile Sites.

Xiaohua Wu

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Xiaohua WuDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA. xiaohwu@scripps.edu.
Scripps Research Institute · US

Funding

Study the mechanisms underlying common fragile site protectionR01CA187052 · NCI · SCRIPPS RESEARCH INSTITUTE, THE · PI WU, XIAOHUA · 2015 to 2025
$4.2M
S-phase checkpoint and rereplication in mammalian cellsR01GM080677 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI WU, XIAOHUA · 2010 to 2018
$2.9M
Role of the Mre11 complex in the maintenance of genome stabilityR01CA197995 · NCI · SCRIPPS RESEARCH INSTITUTE, THE · PI WU, XIAOHUA · 2015 to 2019
$2.2M
NCI NIH HHS R01 CA187052NCI NIH HHS R01 CA197995NIGMS NIH HHS R01 GM080677NIH HHS CA187052NIH HHS CA197995NIH HHS GM080677
6 · The paper itself

Abstract

Rad52 in yeast is a key player in homologous recombination (HR), but mammalian RAD52 is dispensable for HR as shown by the lack of a strong HR phenotype in RAD52-deficient cells and in

Indexed as

break-induced replicationcommon fragile sitesDNA double-strand breaksFANCMhomologous recombinationRAD52replication stress

Identifiers

PMID31569559
PMCPMC6826974
OpenAlexW2976072034

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.