Evidence map›Paper›PMID 31569529›Full record

ArticleNutrients2019

Impregnation of Curcumin into a Biodegradable (Poly-lactic-co-glycolic acid, PLGA) Support, to Transfer Its Well Known In Vitro Effect to an In Vivo Prostate Cancer Model.

Eulalio Gracia, Andrea Mancini, Alessandro Colapietro, Cristina Mateo, Ignacio Gracia, Claudio Festuccia, Manuel Carmona

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Eulalio GraciaInstitute of Chemical and Environmental Technology (ITQUIMA), Department of Chemical Engineering, University of Castilla-La Mancha, 13071 Ciudad Real, Spain. Eulalio.Gracia@uclm.es.
Andrea ManciniLaboratory of Radiobiology, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, 67100 L'Aquila, Italy. mancio_1982@hotmail.com.
Alessandro ColapietroLaboratory of Radiobiology, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, 67100 L'Aquila, Italy. alecolapietro@gmail.com.
Cristina MateoFood Technology Lab, School of Architecture, Engineering and Design, Universidad Europea de Madrid, Villaviciosa de Odón, 28670 Madrid, Spain. cristina.mateo@universidadeuropea.es.
Ignacio GraciaInstitute of Chemical and Environmental Technology (ITQUIMA), Department of Chemical Engineering, University of Castilla-La Mancha, 13071 Ciudad Real, Spain. Ignacio.Gracia@uclm.es.
Claudio FestucciaLaboratory of Radiobiology, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, 67100 L'Aquila, Italy. claudio.festuccia@univaq.it.
Manuel CarmonaFood Technology Lab, School of Architecture, Engineering and Design, Universidad Europea de Madrid, Villaviciosa de Odón, 28670 Madrid, Spain. manuel.carmona@universidadeuropea.es.ORCID 0000-0002-8697-8709
University of L'Aquila · ITUniversidad Europea de Madrid · ESUniversity of Castilla-La Mancha · ES

Funding

Ministerio de Ciencia, Innovación y Universidades Ramón y Cajal Fellowships RyC-2014-16307
6 · The paper itself

Abstract

Prostate cancer (PCa) is one of the most common cancers in older men and is associated with high mortality. Despite advances in screening for early detection of PCa, a large proportion of patients continue to be diagnosed with metastatic disease, with ~20% of men showing a high tumor grade and stage. Medicinal plant extracts have a great potential to prevent/treat PCa, as well as to reduce its incidence/prevalence and improve survival rates. One of the most promising extracts is curcumin, which is a major, nontoxic, bioactive compound of

Indexed as

CapsulesPolylactic Acid-Polyglycolic Acid CopolymerCell Line, TumorCurcuminHumansMalePlant ExtractsProstatic NeoplasmsCapsulesCurcuminPlant ExtractsPolylactic Acid-Polyglycolic Acid Copolymercurcumincurcumin releasemice xenograft modelPLGA polymerprostate cancersupercritical carbon dioxide impregnation

Identifiers

PMID31569529
PMCPMC6835253
OpenAlexW2977035656

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.