ArticleInternational journal of environmental research and public health2019
Computed Tomography Assessment of Brain Atrophy in Centenarians.
Article in International journal of environmental research and public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed, 28 citations in OpenAlex.
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- In search of subcortical and cortical morphologic alterations of a normal brain through aging: an investigation by computed tomography scan.Anatomy & cell biology · 2024Article
- Cortical atrophy in chronic subdural hematoma from ultra-structures to physical properties.Scientific reports · 2023Article
- Observational
- A study of linear measurement and clinical correlation of brain atrophy in Wilson's disease.Frontiers in human neuroscience · 2023Article
- Research on nonstroke dementia screening and cognitive function prediction model for older people based on brain atrophy characteristics.Brain and behavior · 2022Article
- Morphometric study of the ventricular indexes in healthy ovine BRAIN using MRI.BMC veterinary research · 2022Article
- Brain CT can predict low lean mass in the elderly with cognitive impairment: a community-dwelling study.BMC geriatrics · 2022Article
- "Atypical" Mild Clinical Presentation in Elderly Patients With Ruptured Intracranial Aneurysm: Causes and Clinical Characteristics.Frontiers in surgery · 2022Article
- Retained Primitive Reflexes and Potential for Intervention in Autistic Spectrum Disorders.Frontiers in neurology · 2022Review
- Fully Automatic Classification of Brain Atrophy on NCCT Images in Cerebral Small Vessel Disease: A Pilot Study Using Deep Learning Models.Frontiers in neurology · 2022Article
- Severe Encephalatrophy and Related Disorders From Long-Term Ketamine Abuse: A Case Report and Literature Review.Frontiers in psychiatry · 2021Article
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Authors and funding
4 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
The aim of our study was to compare the degree of brain atrophy in centenarians and in seniors 70-99 years old. The study group consisted of 23 patients aged 100-106 years. The control group consisted of 90 patients, 30 in each age subgroup 90-99, 80-89, 70-79. In all the patients, the brain atrophy linear parameters were measured on computed tomography scans, in relation to both "subcortical atrophy", evaluated as progressive widening of the ventricular system, and "cortical atrophy", defined as widening of subarachnoid space. Secondary indices based on the parameters were calculated. Correlations between the above parameters/indices and age were tested. Significantly different values between the centenarians and the control group were found in the brain atrophy parameters: A, B, C, E, FI, ICR, ICL, SW, CFW, F/A 'frontal horn index', A/G 'Evans index', D/A 'ventricular index', H/E 'cella media Schiersmann index', A+B 'Huckman number'. Correlations between parameter/index and age were found for: A, B, C, FI, ICR, ICL, SW, F/A 'frontal horn index', A/G 'Evans index', D/A 'ventricular index', H/E 'cella media Schiersmann index', A+B 'Huckman number'. Brain atrophy associated with aging is a continuously advancing process, affecting centenarians even more than people before the "magic" threshold of 100 years.
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