Evidence map›Paper›PMID 31569423›Full record

ArticleInternational journal of molecular sciences2019

A Molecular Dynamics Study of a Photodynamic Sensitizer for Cancer Cells: Inclusion Complexes of γ-Cyclodextrins with C

Giuseppina Raffaini, Fabio Ganazzoli

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Host-Guest Complexes.International journal of molecular sciences · 2022
    Article
  5. Article
  6. Article
  7. The Physical Chemistry and Chemical Physics (PCCP) Section of theInternational journal of molecular sciences · 2021
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Giuseppina RaffainiDepartment of Chemistry, Materials, and Chemical Engineering "Giulio Natta", Politecnico di Milano, Piazza L. Da Vinci 32, 20131 Milano, Italy. giuseppina.raffaini@polimi.it.ORCID 0000-0003-3462-6514
Fabio GanazzoliDepartment of Chemistry, Materials, and Chemical Engineering "Giulio Natta", Politecnico di Milano, Piazza L. Da Vinci 32, 20131 Milano, Italy. fabio.ganazzoli@polimi.it.ORCID 0000-0002-9762-4535

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photodynamic therapy is an emerging treatment of tumor diseases. The complexes with γ-cyclodextrins (γ-CD) and fullerenes or their derivatives can be used as photosensitizers by direct injection into cancer cells. Using molecular mechanics and molecular dynamics methods, the stability and the geometry of the 2:1 complexes [(γ-CD)

Indexed as

Molecular Dynamics SimulationFullerenesgamma-CyclodextrinsMolecular ConformationPhotochemotherapyPhotosensitizing AgentsSpectrum AnalysisStructure-Activity Relationshipfullerene C70Fullerenesgamma-CyclodextrinsPhotosensitizing Agentsamphiphilic complexesC70cancer therapyfullerenesgamma-cyclodextrininclusion complexesmolecular dynamics simulationsphotodynamic activityphotosensitizersolubilization

Identifiers

PMID31569423
PMCPMC6801912

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.