Evidence map›Paper›PMID 31569370›Full record

ArticleCancers2019

A Functional Analysis of the Unclassified Pro2767Ser BRCA2 Variant Reveals Its Potential Pathogenicity that Acts by Hampering DNA Binding and Homology-Mediated DNA Repair.

Maria Valeria Esposito, Giuseppina Minopoli, Luciana Esposito, Valeria D'Argenio, Federica Di Maggio, Emanuele Sasso, Massimiliano D'Aiuto, Nicola Zambrano, Francesco Salvatore

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Maria Valeria EspositoCEINGE-Biotecnologie Avanzate, 8014 Naples, Italy. espositomari@ceinge.unina.it.
Giuseppina MinopoliCEINGE-Biotecnologie Avanzate, 8014 Naples, Italy. giuseppina.minopoli@unina.it.
Luciana EspositoInstitute of Biostructures and Bioimaging, CNR, Via Mezzocannone 16, I-80134 Naples, Italy. luciana.esposito@unina.it.ORCID 0000-0001-6431-2677
Valeria D'ArgenioCEINGE-Biotecnologie Avanzate, 8014 Naples, Italy. dargenio@ceinge.unina.it.ORCID 0000-0001-9273-3698
Federica Di MaggioCEINGE-Biotecnologie Avanzate, 8014 Naples, Italy. dimaggio@ceinge.unina.it.
Emanuele SassoCEINGE-Biotecnologie Avanzate, 8014 Naples, Italy. sasso@ceinge.unina.it.
Massimiliano D'AiutoDepartment of Senology, Istituto Nazionale Tumori-IRCCS Fondazione Pascale, 80131 Naples, Italy. info@daiuto.it.ORCID 0000-0002-4188-5226
Nicola ZambranoCEINGE-Biotecnologie Avanzate, 8014 Naples, Italy. zambrano@unina.it.ORCID 0000-0001-9395-3481
Francesco SalvatoreCEINGE-Biotecnologie Avanzate, 8014 Naples, Italy. salvator@unina.it.ORCID 0000-0002-2346-3564
Ceinge Biotecnologie Avanzate (Italy) · ITInstitute of Biostructure and Bioimaging · ITIstituto Nazionale Tumori IRCCS "Fondazione G. Pascale" · IT

Funding

Ministero dell'Istruzione, dell'Università e della Ricerca PON03PE_00060_2Ministero dell'Istruzione, dell'Università e della Ricerca PON03PE_00060_7Regione Campania CIRORegione Campania SATIN
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BRCA2breast cancercancer genomicsDNA damage repairmutationvariant of uncertain significance (VUS)VUS classification

Identifiers

PMID31569370
PMCPMC6826418
OpenAlexW2976523055

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.