Evidence map›Paper›PMID 31569345›Full record

ArticleJournal of clinical medicine2019

The Association between Adult Weight Gain and Insulin Resistance at Middle Age: Mediation by Visceral Fat and Liver Fat.

Inge Verkouter, Raymond Noordam, Saskia le Cessie, Rob M van Dam, Hildo J Lamb, Frits R Rosendaal, Diana van Heemst, Renée de Mutsert

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Guideline
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Can Antidiabetic Medications Affect Telomere Length in Patients with Type 2 Diabetes? A Mini-Review.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023
    Review
  14. Antidiabetic and antioxidant potential ofSaudi medical journal · 2022
    Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Inge VerkouterDepartment of Clinical Epidemiology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands. i.verkouter@lumc.nl.ORCID 0000-0003-3374-7840
Raymond NoordamDepartment of Internal Medicine, Section Gerontology and Geriatrics, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands. r.noordam@lumc.nl.
Saskia le CessieDepartment of Clinical Epidemiology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Rob M van DamSaw Swee Hock School of Public Health and Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore 117549, Singapore. rob.van.dam@nus.edu.sg.
Hildo J LambDepartment of Radiology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands. H.J.Lamb@lumc.nl.ORCID 0000-0002-6969-2418
Frits R RosendaalDepartment of Clinical Epidemiology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands. F.R.Rosendaal@lumc.nl.
Diana van HeemstDepartment of Internal Medicine, Section Gerontology and Geriatrics, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands. D.van_Heemst@lumc.nl.ORCID 0000-0001-8526-7748
Renée de MutsertDepartment of Clinical Epidemiology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Leiden University Medical Center · NLNational University of Singapore · SG

Funding

European Commission (HUMAN project) Health-2013-INNOVATION-1-602757Hartstichting CVON2014-02 ENERGISE
6 · The paper itself

Abstract

We aimed to investigate the role of the amount of visceral fat and liver fat in the association between adult weight change and insulin resistance at middle age. In the Netherlands Epidemiology of Obesity study, adult weight change was calculated with recalled body weight at age 20 years and measured body weight at middle age. Measures of insulin resistance were calculated using both fasting and postprandial glucose and insulin concentrations. Visceral fat was assessed by magnetic resonance (MR) imaging and liver fat by proton-MR spectroscopy (

Indexed as

body weight changesfatty liverinsulin resistancevisceral fat

Identifiers

PMID31569345
PMCPMC6832997
OpenAlexW2976244103

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.