Evidence map›Paper›PMID 31569014›Full record

ArticleVirology2019

A cornucopia of Shigella phages from the Cornhusker State.

Sarah M Doore, Jason R Schrad, Hailee R Perrett, Kevin P Schrad, William F Dean, Kristin N Parent

Open access · greenAbstract read
In one paragraph

Article in Virology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. TheJournal of virology · 2025
    Article
  3. Complete genome sequence ofMicrobiology resource announcements · 2025
    Article
  4. Article
  5. Article
  6. Moo19 and B2: Structures ofScience advances · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Ecology, Structure, and Evolution ofAnnual review of virology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sarah M DooreDepartment of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI, 48824, USA; BEACON Center for the Study of Evolution in Action, Michigan State University, East Lansing, MI, 48824, USA.
Jason R SchradDepartment of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI, 48824, USA.
Hailee R PerrettDepartment of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI, 48824, USA.
Kevin P SchradDepartment of Science, Lincoln Southwest High School, Lincoln, NE, 68512, USA.
William F DeanDepartment of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI, 48824, USA.
Kristin N ParentDepartment of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI, 48824, USA; BEACON Center for the Study of Evolution in Action, Michigan State University, East Lansing, MI, 48824, USA. Electronic address: kparent@msu.edu.
Michigan State University · USLincoln Electric (United States) · US

Funding

Training Program in Cell, Molecular, and Developmental BiologyT32GM008111 · NIGMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI YODER, BRADLEY K. · 1985 to 2022
$5.4M
Sf6 as a model system for understanding the mechanisms of virus: host recognitionR01GM110185 · NIGMS · MICHIGAN STATE UNIVERSITY · PI PARENT, KRISTIN N · 2015 to 2019
$1.4M
NIGMS NIH HHS R01 GM110185NIGMS NIH HHS T32 GM008111
6 · The paper itself

Abstract

Bacteriophages are abundant in the environment, yet the vast majority have not been discovered or described. Many characterized bacteriophages infect a small subset of Enterobacteriaceae hosts. Despite its similarity to Escherichia coli, the pathogenic Shigella flexneri has relatively few known phages, which exhibit significant differences from many E. coli phages. This suggests that isolating additional Shigella phages is necessary to further explore these differences. To address questions of novelty and prevalence, high school students isolated bacteriophages on non-pathogenic strains of enteric bacteria. Results indicate that Shigella phages are abundant in the environment and continue to differ significantly from E. coli phages. Our findings suggest that Shigella-infecting members of the Ounavirinae subfamily continue to be over-represented and show surprisingly low diversity within and between sampling sites. Additionally, a podophage with distinct genomic and structural properties suggests that continued isolation on non-model species of bacteria is necessary to truly understand bacteriophage diversity.

Indexed as

AdolescentBacteriophagesFemaleFresh WaterGenome, ViralHumansMaleMyoviridaePhylogenyShigella flexneriSoil MicrobiologyViral ProteinsViral ProteinsAutographivirinaeBacteriophage diversityBacteriophage huntingGenomicsHigh school researchMooglevirusOunavirinaePhylogeneticsShigella bacteriophageVirus ecology

Identifiers

PMID31569014
PMCPMC7009021
OpenAlexW2974557888

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.