ArticleLung cancer (Amsterdam, Netherlands)2019
Consolidation-to-tumor ratio and tumor disappearance ratio are not independent prognostic factors for the patients with resected lung adenocarcinomas.
Article in Lung cancer (Amsterdam, Netherlands), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prognostic value of CT-defined ground-glass opacity in early-stage lung adenocarcinomas: a single-center study and meta-analysis.European radiology · 2024Pooled it
- Prognostic value of consolidation-to-tumor ratio on computed tomography in NSCLC: a meta-analysis.World journal of surgical oncology · 2023Pooled it
- Development and validation of a deep learning signature for predicting lymph node metastasis in lung adenocarcinoma: comparison with radiomics signature and clinical-semantic model.European radiology · 2023Trial
- A Novel Tumor Burden Index to Predict the Prognosis in Stage IA Lung Adenocarcinoma.Annals of surgical oncology · 2026Article
- Is the consolidation-to-tumor ratio an independent prognostic factor in clinical T1 stage lung adenocarcinoma radiologically manifesting as a subsolid nodule?-a retrospective cohort study.Journal of thoracic disease · 2026Article
- The Solid Volume Ratio is Better Than the Consolidation Tumor Ratio in Predicting the Malignant Pathological Features of cT1 Lung Adenocarcinoma.The Thoracic and cardiovascular surgeon · 2025Article
- Prognostic role of subsolid ground-glass opacity, pure ground-glass opacity, and solid nodules of the lung: a retrospective observational study.Journal of thoracic disease · 2025Article
- Prognostic impact ofJournal of thoracic disease · 2024Article
- Tumor size, but not consolidation-to-tumor ratio, is an independent prognostic factor for part-solid clinical T1 non-small cell lung cancer.Thoracic cancer · 2023Review
- Efficacy of a combined tool for stage I non-small cell lung cancer against lymph node metastasis.Oncology letters · 2022Article
- A radiomics nomogram for invasiveness prediction in lung adenocarcinoma manifesting as part-solid nodules with solid components smaller than 6 mm.Frontiers in oncology · 2022Article
- Verification of the eighth edition of the UICC-TNM classification on surgically resected lung adenocarcinoma: Comparison with previous classification in a local center.Cancer reports (Hoboken, N.J.) · 2022Article
- A predictive nomogram for lymph node metastasis in part-solid invasive lung adenocarcinoma: A complement to the IASLC novel grading system.Frontiers in oncology · 2022Article
- Implementation of artificial intelligence in the histological assessment of pulmonary subsolid nodules.Translational lung cancer research · 2021Article
- Tubeless video-assisted thoracic surgery for pulmonary ground-glass nodules: expert consensus and protocol (Guangzhou).Translational lung cancer research · 2021Review
- The importance of being solid for a ground glass opacity of the lung.Annals of translational medicine · 2021Article
- Prognostic histologic subtyping of dominant tumor in resected synchronous multiple adenocarcinomas of lung.Scientific reports · 2021Article
- Narrative review of optimal prognostic radiological tools using computed tomography for T1N0-staged non-small cell lung cancer.Journal of thoracic disease · 2021Review
- Clinical adjustability of radiological tools in patients with surgically resected cT1N0-staged non-small-cell lung cancer from the long-term survival evaluation.Journal of thoracic disease · 2020Article
- Eighth edition T category is prognostic: the size of the solid component matters, not the ratio.Journal of thoracic disease · 2020Article
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Abstract
objectivesOur study aimed to investigate the independent prognostic values of consolidation-to-tumor ratio (CTR) and tumor disappearance ratio (TDR) after adjustment for the conventional prognostic factors and the eighth edition clinical T category for patients with resected lung adenocarcinomas. MATERIALS AND
methodsThis retrospective study included 691 patients (281 men and 410 women; median age, 63 years) with resected lung adenocarcinomas (clinical T1N0M0). The prognostic implications for disease-free survival (DFS) of CTR and TDR in continuous and categorical forms were analyzed using multivariable-adjusted Cox regression analysis, including multiple clinico-radiological prognostic factors and the clinical T category based on the solid portion measurement. Analysis was performed for the total study population and for two part-solid nodule subgroups (cT1mi/cT1a to cT1c and cT1mi/cT1a to cT1b, respectively).
resultsFor the total study population, CTR and TDR were not selected in the multivariable Cox regression models, which indicated that these are not independent prognostic factors. Age (adjusted HR: 1.026; P = 0.022) and clinical T category (adjusted HR for cT1b: 3.475; P = 0.019; adjusted HR for cT1c: 9.938; P < 0.001) were independently associated with DFS. For the part-solid nodule subgroups, multivariable-adjusted HRs for CTR and TDR were not statistically significant (all P > 0.05).
conclusionCTR and TDR were not independent prognostic factors. Preoperative prognostication based on clinical T category would be sufficient without further stratification according to CTR or TDR.
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