Evidence map›Paper›PMID 31568689›Full record

ReviewCancer medicine2019

Operative and peri-operative considerations in the management of brain metastasis.

Eric W Sankey, Vadim Tsvankin, Matthew M Grabowski, Gautam Nayar, Kristen A Batich, Aida Risman, Cosette D Champion, April K S Salama, C Rory Goodwin, Peter E Fecci

Open access · goldAbstract readReview
In one paragraph

Review in Cancer medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
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  8. State-of-the-art application of nanoparticles in radiotherapy: a platform for synergistic effects in cancer treatment.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2025
    Review
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  19. Revisiting the Role of Surgical Resection for Brain Metastasis.Brain tumor research and treatment · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Eric W SankeyDepartment of Neurosurgery, Duke University Medical Center, Durham, NC, USA.
Vadim TsvankinDepartment of Neurosurgery, Duke University Medical Center, Durham, NC, USA.
Matthew M GrabowskiDepartment of Neurosurgery, Cleveland Clinic, Cleveland, OH, USA.
Gautam NayarDepartment of Neurosurgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Kristen A BatichDepartment of Medicine, Duke University Medical Center, Durham, NC, USA.
Aida RismanSchool of Medicine, Medical College of Georgia, Augusta, GA, USA.
Cosette D ChampionDepartment of Neurosurgery, Duke University Medical Center, Durham, NC, USA.ORCID 0000-0001-5140-5196
April K S SalamaDivision of Medical Oncology, Duke University Medical Center, Durham, NC, USA.
C Rory GoodwinDepartment of Neurosurgery, Duke University Medical Center, Durham, NC, USA.
Peter E FecciDepartment of Neurosurgery, Duke University Medical Center, Durham, NC, USA.
Duke Medical Center · USAugusta University · USCleveland Clinic · USUniversity of Pittsburgh Medical Center · US

Funding

Medical Scientist Training Program Training GrantT32GM145449 · NIGMS · DUKE UNIVERSITY · PI Christopher D Kontos · 2022 to 2026
$6.6M
Bristol Myers SquibbBurroughs Wellcome FundCelldexDynavaxGenentechIncyteMerckNIGMS NIH HHS T32 GM145449NIH/NINDS K12 NRCDP Physician Scientist AwardNorth Carolina Spine SocietyReataRobert Wood Johnson Harold Amos Medical Faculty Development Program
6 · The paper itself

Abstract

The number of patients who develop metastatic brain lesions is increasing as the diagnosis and treatment of systemic cancers continues to improve, resulting in longer patient survival. The role of surgery in the management of brain metastasis (BM), particularly multiple and recurrent metastases, remains controversial and continues to evolve. However, with appropriate patient selection, outcomes after surgery are typically favorable. In addition, surgery is the only means to obtain a tissue diagnosis and is the only effective treatment modality to quickly relieve neurological complications or life-threatening symptoms related to significant mass effect, CSF obstruction, and peritumoral edema. As such, a thorough understanding of the role of surgery in patients with metastatic brain lesions, as well as the factors associated with surgical outcomes, is essential for the effective management of this unique and growing patient population.

Indexed as

Brain NeoplasmsCombined Modality TherapyHumansPerioperative Periodcancer managementmetastasisradiation therapysurgical therapy

Identifiers

PMID31568689
PMCPMC6853809
OpenAlexW2977894896

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.