Evidence map›Paper›PMID 31568667›Full record

ArticleInfluenza and other respiratory viruses2020

Genetic diversity of respiratory enteroviruses and rhinoviruses in febrile adults, Singapore, 2007-2013.

Martin Linster, Celeste Donato, Marcus G Mah, Miguel L Grau, Jenny G Low, Eng Eong Ooi, Yvonne C F Su, Gavin J D Smith, Dhanasekaran Vijaykrishna

Abstract read
In one paragraph

Article in Influenza and other respiratory viruses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Enhanced Neutralizing Antibody Responses to Rhinovirus C and Age-Dependent Patterns of Infection.American journal of respiratory and critical care medicine · 2021
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Martin LinsterProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.ORCID 0000-0003-2636-2512
Celeste DonatoDepartment of Microbiology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia.ORCID 0000-0001-9262-6550
Marcus G MahProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.ORCID 0000-0001-8861-7328
Miguel L GrauDepartment of Microbiology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia.
Jenny G LowProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.
Eng Eong OoiProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.ORCID 0000-0002-0520-1544
Yvonne C F SuProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.
Gavin J D SmithProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.ORCID 0000-0001-5031-468X
Dhanasekaran VijaykrishnaProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.ORCID 0000-0003-3293-6279

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To understand the genetic diversity and patterns of circulation of rhinoviruses (RV) and enteroviruses (EV) in Singapore, we retrospectively screened 2950 nasal swab samples collected from adults presenting to primary care services with signs of febrile illness in Singapore during 2007-2013 using sequencing and phylogenetic methods. Through sequencing and phylogenetic analysis, our results show the year-round circulation of the three rhinovirus species, A, B, and C. A diverse set of RV/EV serotypes were detected in Singapore with a predominance of RV-A in all years, whereas serotypes EV-C A21 and EV-D68 were only sporadically detected. This study highlights the previously unrecognized diversity and burden in the adult population in Singapore.

Indexed as

Genetic VariationAdolescentAdultAgedEnterovirusEnterovirus InfectionsFemaleFeverHumansMaleMiddle AgedPhylogenyPicornaviridae InfectionsRetrospective StudiesRhinovirusSeasonsenterovirusfebrile illnessphylogenetic analysisrhinovirusserotypesSingaporevirus diversity

Identifiers

PMID31568667
PMCPMC6928033

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.