Evidence map›Paper›PMID 31568612›Full record

ArticleJournal of clinical laboratory analysis2020

Therapeutic effect of high-frequency ultrasound-assisted dye laser on hemangioma and its influence on serum HIF-1α in patients.

Hongzhang Hu, Pengyuan Song, Jinyan Yang, Xia Wang, Zhaohui Chen, Jianhua Fang

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical laboratory analysis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Hongzhang HuDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, China.
Pengyuan SongDepartment of Ultrasound, The Second Affiliated Hospital of Xinjiang Medical University, Urumqi, China.
Jinyan YangDepartment of Dermatology, The Second Affiliated Hospital of Xinjiang Medical University, Urumqi, China.
Xia WangDepartment of Ultrasound, The Second Affiliated Hospital of Xinjiang Medical University, Urumqi, China.
Zhaohui ChenDepartment of Dermatology, The Second Affiliated Hospital of Xinjiang Medical University, Urumqi, China.
Jianhua FangDepartment of Ultrasonography, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, China.ORCID https://orcid.org/0000-0002-7966-7443
Xinjiang Medical University · CNHangzhou First People's Hospital · CNSichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo analyze the therapeutic effect of high-frequency ultrasound (HFU)-assisted dye laser on hemangioma patients and changes in serum hypoxia-inducible factor-1α (HIF-1α).

methodsA total of 20 patients diagnosed with hemangioma in our hospital from January 2013 to March 2018 were selected, including 12 males and eight females. All patients were treated with HFU-assisted dye laser. The site and type of hemangioma and age distribution of patients were collected, and changes in data and area of hemangioma and serum HIF-1α before and after treatment were analyzed.

resultsThe vascular condition of hemangioma in all patients was significantly improved at 7, 14, and 30 days after treatment. Gray-scale ultrasound displayed that the tumor area was reduced by more than 50%. After treatment, the serum HIF-1α level declined obviously after treatment compared with that before treatment, showing a statistically significant difference (P < 0.05).

conclusionHFU-assisted dye laser can effectively reduce the tumor area, decrease the serum HIF-1α level, and improve the prognosis in the treatment of hemangioma.

Indexed as

UltrasonicsAdolescentAdultChildChild, PreschoolFemaleHemangiomaHumansHypoxia-Inducible Factor 1, alpha SubunitInfantLasers, DyeMaleYoung AdultHIF1A protein, humanHypoxia-Inducible Factor 1, alpha SubunithemangiomaHFUHIF-1αlaser

Identifiers

PMID31568612
PMCPMC6977139
OpenAlexW2978625415

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.