ArticlePLoS neglected tropical diseases2019
The association of depression, anxiety, and stress with caring for a child with Congenital Zika Syndrome in Brazil; Results of a cross-sectional study.
Article in PLoS neglected tropical diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
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Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Measuring the global burden of chikungunya and Zika viruses: A systematic review.PLoS neglected tropical diseases · 2021Pooled it
- Congenital Zika Syndrome-Assessing the Need for a Family Support Programme in Brazil.International journal of environmental research and public health · 2020Pooled it
- Zika Virus Inoculation During Pregnancy Impaired Maternal Care and Altered Prolactin and Corticosterone Levels in Rats.Developmental neurobiology · 2026Article
- Responsive population-based cohorts as platforms for characterising pathogen- and population-level infection dynamics for epidemic prevention, preparedness and response.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025Article
- Perception of Quality of Life by Primary Caregivers of Children with Congenital Zika Syndrome: a Cross-Sectional Study.Maternal and child health journal · 2025Article
- The perceived COVID-19 pandemic risk and mental distress in China: the mediating role of interpersonal trust and the moderating role of social cohesion.Frontiers in psychology · 2025Article
- Understanding the multidimensional neurodevelopmental outcomes in children after congenital Zika virus exposure.Pediatric research · 2024Review
- Factors Associated with Behavioral Disorders in Children with Congenital Zika Syndrome and Their Families-A Cross-Sectional Study.International journal of environmental research and public health · 2022Article
- "One feels anger to know there is no one to help us!". Perceptions of mothers of children with Zika virus-associated microcephaly in Caribbean Colombia: A qualitative study.PLoS neglected tropical diseases · 2022Article
- Quality of life, depressive symptoms, anxiety, and sexual function in mothers of neonates with congenital syphilis in the Northeast Brazil: A cohort study.Lancet regional health. Americas · 2022Article
- Congenital Zika Syndrome: Genetic Avenues for Diagnosis and Therapy, Possible Management and Long-Term Outcomes.Journal of clinical medicine · 2022Review
- Article
- Assessment of the feasibility of Juntos: A support programme for families of children affected by Congenital Zika Syndrome.Wellcome open research · 2022Article
- Anxiety, depression, and quality of life in mothers of children with congenital Zika syndrome: Results of a 5-year follow-up study.Revista da Sociedade Brasileira de Medicina Tropical · 2022Article
- Participatory Visual Methods with caregivers of children with Congenital Zika Syndrome in Colombia: A case study.Wellcome open research · 2022Article
- The legacy of ZikaPLAN: a transnational research consortium addressing Zika.Global health action · 2021Review
- Epidemic preparedness: Prenatal Zika virus screening during the next epidemic.BMJ global health · 2021Review
- The feasibility of establishing parent support groups for children with congenital Zika syndrome and their families: a mixed-methods study.Wellcome open research · 2021Article
- Perceptions and Emotional State of Mothers of Children with and without Microcephaly after the Zika Virus Epidemic in Rural Caribbean Colombia.Behavioral sciences (Basel, Switzerland) · 2020Article
- The promise and pitfalls of social science research in an emergency: lessons from studying the Zika epidemic in Brazil, 2015-2016.BMJ global health · 2020Review
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
backgroundZika virus (ZIKV) infection in pregnancy can cause microcephaly and a wide spectrum of severe adverse outcomes, collectively called "Congenital Zika Syndrome" (CZS). Parenting a child with disabilities can have adverse mental health impacts, but these associations have not been fully explored in the context of CZS in Brazil. METHODOLOGY/PRINCIPAL
findingsA cross-sectional study was undertaken in Recife and Rio de Janeiro, including 163 caregivers of a child with CZS (cases) and 324 caregivers with an unaffected child (comparison subjects), identified from existing studies. The primary caregiver, almost always the mother, was interviewed using a structured questionnaire to collect information on: depression, anxiety, and stress (Depression, Anxiety, and Stress Scale-DASS-21), social support (Medical Outcomes Study Social Support Scale-MOS-SSS), and socio-demographic data. Data was collected May 2017-January 2018. Ethical standards were adhered to throughout the research. A high proportion of mothers reported experiencing severe or extremely severe levels of depression (18%), anxiety (27%) and stress (36%). Mothers of children with CZS were more likely to experience symptoms of depression, anxiety andstress, compared to mothers of comparison children. These associations were more apparent among mothers living in Rio de Janeiro. These differences were reduced after adjustment for socio-economic status and social support. Among mothers of children with CZS, low social support was linked to higher levels of depression, anxiety and stress, but there was no association with socio-economic status. CONCLUSIONS/SIGNIFICANCE: Depression, anxiety and stress were very common among mothers of young children in Brazil, regardless of whether they were parenting a child with disabilities. Mothers of children with CZS may be particularly vulnerable to poor mental health, and this association may be buffered through better social support.
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