Evidence map›Paper›PMID 31567654›Full record

ArticleSexually transmitted diseases2020

Recent Penile Sexual Contact Is Associated With an Increased Odds of High-Risk Cervical Human Papillomavirus Infection in Transgender Men.

Madeline B Deutsch, Sari L Reisner, Sarah Peitzmeier, Jennifer Potter, Dana Pardee, Jaclyn M W Hughto

Open access · greenAbstract read
In one paragraph

Article in Sexually transmitted diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Madeline B DeutschFrom the Department of Family & Community Medicine, University of California, San Francisco, CA.
Sari L Reisner
Sarah PeitzmeierSchool of Nursing, Department of Health Behavior and Biological Sciences, University of Michigan, Ann Arbor, MI.
Jennifer Potter
Dana PardeeThe Fenway Institute, Fenway Health.
Jaclyn M W Hughto
Fenway Health · USBoston Children's Hospital · USUniversity of California, San Francisco · USUniversity of Michigan–Ann Arbor · US

Funding

Project 4: Neonatal Abstinence Syndrome (NAS): Fetus to First YearsP20GM125507 · NIGMS · RHODE ISLAND HOSPITAL · PI JOSIAH D RICH · 2018 to 2026
$23.4M
Midcareer Investigator Award in Patient Oriented ResearchK24DA022112 · NIDA · MIRIAM HOSPITAL · PI RICH, JOSIAH D · 2008 to 2017
$1.7M
Intervention to Overcome Mental Health Disparities in Criminally-Justice Involved Transgender WomenF31MD011203 · NIMHD · YALE UNIVERSITY · PI HUGHTO, JACLYN WHITE · 2016 to 2017
$88k
NIDA NIH HHS K24 DA022112NIGMS NIH HHS P20 GM125507NIMHD NIH HHS F31 MD011203
6 · The paper itself

Abstract

backgroundTransgender men (TM) have a male, masculine, or nonfemale gender identity, yet were assigned female sex at birth on the basis of their external genitalia. The majority of TM are at risk of infection with one of several high-risk strains of the human papillomavirus (hr-HPV), acquired primarily through sexual contact, that cause 99.7% of cervical cancers. This study aimed to explore the association between sexual behaviors and current cervical hr-HPV infection in TM with a cervix.

methodsThe primary aim of this analysis was to test for an association between participant self-report of sexual contact with a penis in the past 1 year and current infection with cervical hr-HPV as measured by provider-collected cervical HPV DNA assay. This is a secondary analysis of a bio-behavioral sexual health study conducted at a health center in Boston, MA from 2015 to 2016. Analysis was conducted using logistic regression with significance level set at P less than 0.05; the primary analysis was adjusted for self-reported age, current tobacco use, years of testosterone use, and HPV vaccination status.

resultsOverall prevalence of hr-HPV was 15.9%. In adjusted analyses, participants reporting receptive penile vaginal sex with any of their most recent 3 sexual partners in the past 12 months had more than 5 times greater odds of current hr-HPV infection than those reporting no penile sex of any kind during this timeframe (odds ratio, 5.23; 95% confidence interval, 1.61-17.02).

conclusionsVaginal-receptive penile sex in the last 12 months was associated with a 5-fold increased odds of cervical high-risk HPV infection among TM. Findings can inform future population level study of associations between sexual behaviors and hr-HPV risk, which could lead to more individualized approaches to screening.

Indexed as

Sexual BehaviorTransgender PersonsAdultCervix UteriDNA, ViralFemaleHumansMaleMiddle AgedOdds RatioPapillomaviridaePapillomavirus InfectionsPenisPrevalenceRisk FactorsSurveys and QuestionnairesDNA, Viral

Identifiers

PMID31567654
PMCPMC7357237
OpenAlexW2977384410

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.