Evidence map›Paper›PMID 31567074›Full record

ArticleIEEE transactions on medical imaging2020

Software-Based Phase Control, Video-Rate Imaging, and Real-Time Mosaicing With a Lissajous-Scanned Confocal Microscope.

Nathan O Loewke, Zhen Qiu, Michael J Mandella, Robert Ertsey, Adrienne Loewke, Lisa A Gunaydin, Eben L Rosenthal, Christopher H Contag, Olav Solgaard

Abstract read
In one paragraph

Article in IEEE transactions on medical imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. CRASH2p: Closed-loop Two Photon Imaging in a Freely Moving Animal.bioRxiv : the preprint server for biology · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Image processing metrics for phase identification of a multiaxis MEMS scanner used in single pixel imaging.IEEE/ASME transactions on mechatronics : a joint publication of the IEEE Industrial Electronics Society and the ASME Dynamic Systems and Control Division · 2021
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nathan O Loewke
Zhen Qiu
Michael J Mandella
Robert Ertsey
Adrienne Loewke
Lisa A Gunaydin
Eben L Rosenthal
Christopher H Contag
Olav Solgaard

Funding

Dynamic Imaging of EMT in the Breast Cancer MicroenvironmentR01CA172895 · NCI · STANFORD UNIVERSITY · PI CONTAG, CHRISTOPHER H · 2013 to 2017
$3.2M
(PQC2)High-content Pathology with Confocal Microscope ArraysR01CA180152 · NCI · STANFORD UNIVERSITY · PI RIMM, DAVID L, SOLGAARD, OLAV · 2013 to 2016
$2.5M
NCI NIH HHS R01 CA172895NCI NIH HHS R01 CA180152
6 · The paper itself

Abstract

We present software-based methods for automatic phase control and for mosaicing high-speed, Lissajous-scanned images. To achieve imaging speeds fast enough for mosaicing, we first increase the image update rate tenfold from 3 to 30 Hz, then vertically interpolate each sparse image in real-time to eliminate fixed pattern noise. We validate our methods by imaging fluorescent beads and automatically maintaining phase control over the course of one hour. We then image fixed mouse brain tissues at varying update rates and compare the resulting mosaics. Using reconstructed image data as feedback for phase control eliminates the need for phase sensors and feedback controllers, enabling long-term imaging experiments without additional hardware. Mosaicing subsampled images results in video-rate imaging speeds, nearly fully recovered spatial resolution, and millimeter-scale fields of view.

Indexed as

SoftwareAlgorithmsAnimalsBrainImage Processing, Computer-AssistedMiceMicroscopy, ConfocalVideo Recording

Identifiers

PMID31567074
PMCPMC8837204

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.