Evidence map›Paper›PMID 31566462›Full record

ArticleJournal of the American Heart Association2019

Metabolic Activity in Central Neural Structures of Patients With Myocardial Injury.

Michael Fiechter, Andrea Roggo, Achi Haider, Susan Bengs, Irene A Burger, Monika Marędziak, Angela Portmann, Valerie Treyer, Anton S Becker, Michael Messerli and 10 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

  1. Systemic brain-body metabolic coupling patterns in amyotrophic lateral sclerosis: a whole-body [European journal of nuclear medicine and molecular imaging · 2026
    Article
  2. Metabolism-Mediated Regulation of Brain-Heart Interactions.International journal of molecular sciences · 2026
    Review
  3. The importance of genetic counselling for turner syndrome transition.European child & adolescent psychiatry · 2025
    Review
  4. Exploring the Relationship Between Heart, Brain, and Depression.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2025
    Review
  5. Article
  6. Review
  7. Assessment of cerebral glucose metabolism in patients with heart failure byJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 2 institutions in 1 country.

Michael FiechterDepartment of Nuclear Medicine University Hospital Zurich Zurich Switzerland.
Andrea RoggoDepartment of Nuclear Medicine University Hospital Zurich Zurich Switzerland.
Achi HaiderDepartment of Nuclear Medicine University Hospital Zurich Zurich Switzerland.
Susan BengsDepartment of Nuclear Medicine University Hospital Zurich Zurich Switzerland.
Irene A BurgerDepartment of Nuclear Medicine University Hospital Zurich Zurich Switzerland.
Monika MarędziakDepartment of Nuclear Medicine University Hospital Zurich Zurich Switzerland.
Angela PortmannDepartment of Nuclear Medicine University Hospital Zurich Zurich Switzerland.
Valerie TreyerDepartment of Nuclear Medicine University Hospital Zurich Zurich Switzerland.
Anton S BeckerDepartment of Diagnostic and Interventional Radiology University Hospital Zurich Zurich Switzerland.
Michael MesserliDepartment of Nuclear Medicine University Hospital Zurich Zurich Switzerland.
Urs J MühlematterDepartment of Diagnostic and Interventional Radiology University Hospital Zurich Zurich Switzerland.
Ken KuduraDepartment of Nuclear Medicine University Hospital Zurich Zurich Switzerland.
Elia von FeltenDepartment of Nuclear Medicine University Hospital Zurich Zurich Switzerland.
Dominik C BenzDepartment of Nuclear Medicine University Hospital Zurich Zurich Switzerland.
Tobias A FuchsDepartment of Nuclear Medicine University Hospital Zurich Zurich Switzerland.
Christoph GräniDepartment of Nuclear Medicine University Hospital Zurich Zurich Switzerland.
Aju P PazhenkottilDepartment of Nuclear Medicine University Hospital Zurich Zurich Switzerland.
Ronny R BuechelDepartment of Nuclear Medicine University Hospital Zurich Zurich Switzerland.
Philipp A KaufmannDepartment of Nuclear Medicine University Hospital Zurich Zurich Switzerland.
Catherine GebhardDepartment of Nuclear Medicine University Hospital Zurich Zurich Switzerland.
University Hospital of Zurich · CHUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Increasing evidence suggests a psychosomatic link between neural systems and the heart. In light of the growing burden of ischemic cardiovascular disease across the globe, a better understanding of heart-brain interactions and their implications for cardiovascular treatment strategies is needed. Thus, we sought to investigate the interaction between myocardial injury and metabolic alterations in central neural areas in patients with suspected or known coronary artery disease. Methods and Results The association between resting metabolic activity in distinct neural structures and cardiac function was analyzed in 302 patients (aged 66.8±10.2 years; 70.9% men) undergoing fluor-18-deoxyglucose positron emission tomography and

Indexed as

Energy MetabolismAgedBrainCoronary Artery DiseaseFemaleHumansMaleMiddle AgedMyocardial Perfusion ImagingMyocardiumPositron Emission Tomography Computed TomographyRetrospective StudiesRisk FactorsSex FactorsStroke VolumeTomography, Emission-Computed, Single-Photonbrainstemcaudate nucleuscorpus callosumfluor‐18‐deoxyglucose positron emission tomography/computed tomographymyocardial perfusion imagingnervous system, autonomicsex

Identifiers

PMID31566462
PMCPMC6806042
OpenAlexW2976275089

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.