Evidence map›Paper›PMID 31566435›Full record

ArticleAmerican journal of physiology. Renal physiology2019

AMPK phosphorylation of the β

Pei-Yin Ho, Hui Li, Lei Cheng, Vivek Bhalla, Robert A Fenton, Kenneth R Hallows

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Renal physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. The Epithelial Sodium Channel-An Underestimated Drug Target.International journal of molecular sciences · 2023
    Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Pei-Yin HoDivision of Nephrology and Hypertension, Department of Medicine and USC/UKRO Kidney Research Center, Keck School of Medicine, University of Southern California, Los Angeles, California.
Hui LiDivision of Nephrology and Hypertension, Department of Medicine and USC/UKRO Kidney Research Center, Keck School of Medicine, University of Southern California, Los Angeles, California.
Lei ChengDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.
Vivek BhallaDivision of Nephrology, Department of Medicine, Stanford University School of Medicine, Stanford, California.
Robert A FentonDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.
Kenneth R HallowsDivision of Nephrology and Hypertension, Department of Medicine and USC/UKRO Kidney Research Center, Keck School of Medicine, University of Southern California, Los Angeles, California.
University of Southern California · USAarhus University · DKStanford University · US

Funding

Mechanisms and Relevance of Sodium Transport Regulation by AMPKR01DK075048 · NIDDK · UNIVERSITY OF SOUTHERN CALIFORNIA · PI HALLOWS, KENNETH R · 2007 to 2015
$2.5M
ENaC Transport in Insulin Resistance: Role of Insulin & IGF-1 ReceptorsR01DK091565 · NIDDK · STANFORD UNIVERSITY · PI BHALLA, VIVEK · 2011 to 2015
$2.0M
NIDDK NIH HHS R01 DK075048NIDDK NIH HHS R01 DK091565
6 · The paper itself

Abstract

The metabolic sensor AMP-activated protein kinase (AMPK) inhibits the epithelial Na

Indexed as

14-3-3 ProteinsAMP-Activated Protein KinasesAnimalsEpithelial CellsEpithelial Sodium ChannelsGene Expression Regulation, EnzymologicHEK293 CellsHumansKidneyKidney Tubules, CollectingMiceMutationNedd4 Ubiquitin Protein LigasesPhosphorylationRho Guanine Nucleotide Exchange Factors14-3-3 ProteinsAMP-Activated Protein KinasesARHGEF7 protein, humanEpithelial Sodium ChannelsNedd4 Ubiquitin Protein LigasesRho Guanine Nucleotide Exchange Factors14-3-3 proteinAMP-activated protein kinaseepithelial Na+ channelneural precursor cell expressed developmentally downregulated protein 4-2p21-activated kinase-interacting exchange factor-β1

Identifiers

PMID31566435
PMCPMC6962512
OpenAlexW2977391065

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.