Evidence map›Paper›PMID 31566433›Full record

ArticleAmerican journal of physiology. Renal physiology2019

Yoshihiro Akimoto, Kunimasa Yan, Yuri Miura, Hiroki Tsumoto, Tosifusa Toda, Toshiyuki Fukutomi, Daisuke Sugahara, Akihiko Kudo, Tomio Arai, Yuko Chiba and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 19 citations in OpenAlex.

  1. Post‑translational modifications in diabetic kidney disease (Review).International journal of molecular medicine · 2026
    Review
  2. December In focus in HCB.Histochemistry and cell biology · 2025
    Article
  3. Article
  4. Glycosylation in kidney diseases.Precision clinical medicine · 2025
    Review
  5. Immunohistochemical Study onActa histochemica et cytochemica · 2025
    Review
  6. Review
  7. Article
  8. The O-GlcNAc dichotomy: when does adaptation become pathological?Clinical science (London, England : 1979) · 2023
    Review
  9. International journal of oncology · 2023
    Article
  10. ProteinMetabolites · 2022
    Review
  11. Cells · 2022
    Review
  12. Role ofPhysiological reviews · 2021
    Review
  13. Altered Actin Dynamics in Cell Migration of GNE Mutant Cells.Frontiers in cell and developmental biology · 2021
    Article
  14. Review
  15. Regulation of actin isoforms in cellular and developmental processes.Seminars in cell & developmental biology · 2020
    Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Yoshihiro AkimotoDepartment of Anatomy, Kyorin University School of Medicine, Mitaka, Tokyo, Japan.
Kunimasa YanDepartment of Pediatrics, Kyorin University School of Medicine, Mitaka, Tokyo, Japan.
Yuri MiuraResearch Team for Mechanism of Aging, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan.
Hiroki TsumotoResearch Team for Mechanism of Aging, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan.
Tosifusa TodaResearch Team for Mechanism of Aging, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan.
Toshiyuki FukutomiDepartment of Pharmacology and Toxicology, Kyorin University School of Medicine, Mitaka, Tokyo, Japan.
Daisuke SugaharaDepartment of Anatomy, Kyorin University School of Medicine, Mitaka, Tokyo, Japan.
Akihiko KudoDepartment of Anatomy, Kyorin University School of Medicine, Mitaka, Tokyo, Japan.
Tomio AraiDepartment of Pathology, Tokyo Metropolitan Geriatric Hospital, Itabashi, Tokyo, Japan.
Yuko ChibaDepartment of Diabetes, Metabolism and Endocrinology, Tokyo Metropolitan Geriatric Hospital, Itabashi, Tokyo, Japan.
Shinya KanameDepartment of Nephrology and Rheumatology, Kyorin University School of Medicine, Mitaka, Tokyo, Japan.
Gerald W HartCenter for Complex Carbohydrates, University of Georgia, Athens, Georgia.
Tamao EndoResearch Team for Mechanism of Aging, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan.
Hayato KawakamiDepartment of Anatomy, Kyorin University School of Medicine, Mitaka, Tokyo, Japan.
Kyorin University · JPTokyo Metropolitan Institute of Gerontology · JPTokyo Metropolitan Geriatric Hospital · JPUniversity of Georgia · US

Funding

Cytosolic O-Glycosylation and Insulin SignalingR01DK061671 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI HART, GERALD WARREN · 2002 to 2014
$4.0M
Nutrient Regulation of Cell Physiology by O-GlcNAcylationR01GM116891 · NIGMS · UNIVERSITY OF GEORGIA · PI HART, GERALD WARREN · 2016 to 2023
$2.4M
NIDDK NIH HHS R01 DK061671NIGMS NIH HHS R01 GM116891
6 · The paper itself

Abstract

The function of actin is regulated by various posttranslational modifications. We have previously shown that in the kidneys of nonobese type 2 diabetes model Goto-Kakizaki rats, increased

Indexed as

ActinsAcylationAmino Acid SequenceAnimalsDiabetes Mellitus, Type 2Diabetic NephropathiesHumansKidneyMaleModels, MolecularPhosphorylationPodocytesProtein ConformationRatsRats, Inbred StrainsActinsdiabetic nephropathyGoto-Kakizaki ratO-GlcNAcylationphosphorylation and dephosphorylationβ-actin

Identifiers

PMID31566433
PMCPMC6879942
OpenAlexW2979025765

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.