Evidence map›Paper›PMID 31566355›Full record

ArticleBiochemistry2019

Retinoic Acid Binding Leads to CRABP2 Rigidification and Dimerization.

Carolina Lixa, Michael W Clarkson, Anwar Iqbal, Thomas M Moon, Fabio C L Almeida, Wolfgang Peti, Anderson S Pinheiro

Abstract read
In one paragraph

Article in Biochemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. AllJournal of the Royal Society, Interface · 2025
    Article
  5. Studies of All-trans Retinoic Acid Transport in the Eye.Investigative ophthalmology & visual science · 2025
    Article
  6. Molecular Stiffening by Macrocycle Clustering.Angewandte Chemie (International ed. in English) · 2025
    Article
  7. Article
  8. Article
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  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Carolina LixaDepartment of Biochemistry, Institute of Chemistry , Federal University of Rio de Janeiro , Rio de Janeiro , RJ 21941909 , Brazil.
Michael W ClarksonDepartment of Chemistry and Biochemistry, College of Medicine , University of Arizona , Tucson , Arizona 85721 , United States.
Anwar IqbalNational Center for Nuclear Magnetic Resonance Jiri Jonas, Institute of Medical Biochemistry , Federal University of Rio de Janeiro , Rio de Janeiro , RJ 21941902 , Brazil.
Thomas M MoonDepartment of Chemistry and Biochemistry, College of Medicine , University of Arizona , Tucson , Arizona 85721 , United States.
Fabio C L AlmeidaNational Center for Nuclear Magnetic Resonance Jiri Jonas, Institute of Medical Biochemistry , Federal University of Rio de Janeiro , Rio de Janeiro , RJ 21941902 , Brazil.ORCID 0000-0001-6046-7006
Wolfgang PetiDepartment of Chemistry and Biochemistry, College of Medicine , University of Arizona , Tucson , Arizona 85721 , United States.ORCID 0000-0002-8830-6594
Anderson S PinheiroDepartment of Biochemistry, Institute of Chemistry , Federal University of Rio de Janeiro , Rio de Janeiro , RJ 21941909 , Brazil.ORCID 0000-0001-5118-6931
Universidade Federal do Rio de Janeiro · BRUniversity of Arizona · US

Funding

Protein Phosphatase 1 Holoenzyme Formation and Subunit ExchangeR01GM134683 · NIGMS · UNIVERSITY OF ARIZONA · PI PETI, WOLFGANG · 2019 to 2020
$564k
NIGMS NIH HHS R01 GM134683
6 · The paper itself

Abstract

Cellular retinoic acid-binding protein 2 (CRABP2) delivers

Indexed as

Protein MultimerizationCell NucleusCrystallizationEntropyEscherichia coliHumansHydrophobic and Hydrophilic InteractionsKineticsLigandsMagnetic Resonance SpectroscopyProtein BindingProtein Structure, SecondaryReceptors, Retinoic AcidTretinoinLigandsReceptors, Retinoic Acidretinoic acid binding protein II, cellularTretinoin

Identifiers

PMID31566355
PMCPMC13047426
OpenAlexW2977873031

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.