Evidence map›Paper›PMID 31566148›Full record

ArticlePublic health nutrition2020

Adherence to the Dietary Approaches to Stop Hypertension (DASH) diet is associated with lower presence of non-alcoholic fatty liver disease in middle-aged and elderly adults.

Mian-Li Xiao, Jie-Sheng Lin, Yi-Hong Li, Meng Liu, Yun-Yang Deng, Chang-Yi Wang, Yu-Ming Chen

Open access · greenAbstract read
In one paragraph

Article in Public health nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.

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  10. Nutritional and Fasting Strategies for the Management of MASLD/MASH: An Integrative Review.JGH open : an open access journal of gastroenterology and hepatology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Mian-Li XiaoGuangdong Provincial Key Laboratory of Food, Nutrition and Health, and Department of Medical Statistics & Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou 510080, People's Republic of China.
Jie-Sheng LinGuangdong Provincial Key Laboratory of Food, Nutrition and Health, and Department of Medical Statistics & Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou 510080, People's Republic of China.
Yi-Hong LiGuangdong Provincial Key Laboratory of Food, Nutrition and Health, and Department of Medical Statistics & Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou 510080, People's Republic of China.
Meng LiuGuangdong Provincial Key Laboratory of Food, Nutrition and Health, and Department of Medical Statistics & Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou 510080, People's Republic of China.
Yun-Yang DengGuangdong Provincial Key Laboratory of Food, Nutrition and Health, and Department of Medical Statistics & Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou 510080, People's Republic of China.
Chang-Yi WangDepartment of Non-communicable Disease Prevention and Control, Shenzhen Nanshan Center for Chronic Disease Control, Shenzhen 518054, People's Republic of China.
Yu-Ming ChenGuangdong Provincial Key Laboratory of Food, Nutrition and Health, and Department of Medical Statistics & Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou 510080, People's Republic of China.ORCID 0000-0003-1658-5528
Sun Yat-sen University · CNShenzhen Nanshan Center for Chronic Disease Control · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePrevious studies have shown that the Dietary Approaches to Stop Hypertension (DASH) diet might contribute to managing risk factors of non-alcoholic fatty liver disease (NAFLD), but evidence is limited. We examined the association of DASH diet score (DASH-DS) with NAFLD, as well as the intermediary effects of serum retinol-binding protein-4 (RBP4), serum high-sensitivity C-reactive protein (hs-CRP), serum TAG, homeostasis model assessment of insulin resistance (HOMA-IR) and BMI.

designWe performed a cross-sectional analysis of a population-based cohort study. Dietary data and lifestyle factors were assessed by face-to-face interviews and the DASH-DS was then calculated. We assessed serum RBP4, hs-CRP and TAG and calculated HOMA-IR. The presence and degree of NAFLD were determined by abdominal sonography.

settingGuangzhou, China.

participantsGuangzhou Nutrition and Health Study participants, aged 40-75 years at baseline (n 3051).

resultsAfter adjusting for potential covariates, we found an inverse association between DASH-DS and the presence of NAFLD (Ptrend = 0·009). The OR (95 % CI) of NAFLD for quintiles 2-5 were 0·78 (0·62, 0·98), 0·74 (0·59, 0·94), 0·69 (0·55, 0·86) and 0·77 (0·61, 0·97), respectively. Path analyses indicated that a higher DASH-DS was associated with lower serum RBP4, hs-CRP, TAG, HOMA-IR and BMI, which were positively associated with the degree of NAFLD.

conclusionsAdherence to the DASH diet was independently associated with a marked lower prevalence of NAFLD in Chinese adults, especially in women and those without abdominal obesity, and might be mediated by reducing RBP4, hs-CRP, TAG, HOMA-IR and BMI.

Indexed as

AdultAgedBlood GlucoseChinaC-Reactive ProteinCross-Sectional StudiesDietary Approaches To Stop HypertensionFemaleHumansMaleMiddle AgedNon-alcoholic Fatty Liver DiseaseNutrition SurveysPatient CompliancePrevalenceRetinol-Binding Proteins, PlasmaBlood GlucoseC-Reactive ProteinRBP4 protein, humanRetinol-Binding Proteins, PlasmaTriglyceridesCross-sectional studyDietary Approaches to Stop Hypertension dietNon-alcoholic fatty liver diseaseNutrition

Identifiers

PMID31566148
PMCPMC10200450
OpenAlexW2977575656

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.