Evidence map›Paper›PMID 31566091›Full record

ArticleJournal of toxicology and environmental health. Part A2019

Cardiovascular effects of diesel exhaust inhalation: photochemically altered versus freshly emitted in mice.

Haiyan Tong, Jose Zavala, Rachel McIntosh-Kastrinsky, Kenneth G Sexton

Open access · greenAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of toxicology and environmental health. Part A, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Haiyan TongEnvironmental Public Health Division, NHEERL, US Environmental Protection Agency, Research Triangle Park , Durham , NC , USA.
Jose ZavalaDepartment of Environmental Sciences and Engineering, Gilling's School of Global Public Health, University of North Carolina at Chapel Hill , Chapel Hill , NC , USA.ORCID 0000-0001-8286-6577
Rachel McIntosh-KastrinskyDepartment of Environmental Sciences and Engineering, Gilling's School of Global Public Health, University of North Carolina at Chapel Hill , Chapel Hill , NC , USA.
Kenneth G SextonDepartment of Environmental Sciences and Engineering, Gilling's School of Global Public Health, University of North Carolina at Chapel Hill , Chapel Hill , NC , USA.
University of North Carolina at Chapel Hill · USEnvironmental Protection Agency · US

Funding

Intramural EPA EPA999999
6 · The paper itself

Abstract

This study was designed to compare the cardiovascular effects of inhaled photochemically altered diesel exhaust (aged DE) to freshly emitted DE (fresh DE) in female C57Bl/6 mice. Mice were exposed to either fresh DE, aged DE, or filtered air (FA) for 4 hr using an environmental irradiation chamber. Cardiac responses were assessed 8 hr after exposure utilizing Langendorff preparation with a protocol consisting of 20 min of perfusion and 20 min of ischemia followed by 2 hr of reperfusion. Cardiac function was measured by indices of left-ventricular-developed pressure (LVDP) and contractility (dP/dt) prior to ischemia. Recovery of post-ischemic LVDP was examined on reperfusion following ischemia. Fresh DE contained 460 µg/m

Indexed as

AdultAir PollutantsAnimalsCardiovascular SystemEnvironmental ExposureFemaleHeart Function TestsHumansInhalation ExposureMaleMiceMiddle AgedOxidants, PhotochemicalParticulate MatterUnited StatesVehicle EmissionsAir PollutantsOxidants, PhotochemicalParticulate MatterVehicle Emissionscardiac functionDiesel exhaustphotochemistry

Identifiers

PMID31566091
PMCPMC7308149
OpenAlexW2978031786

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.