Evidence map›Paper›PMID 31566067›Full record

ArticleJournal of the American Heart Association2019

Nocturnal Mean Arterial Pressure Rising Is Associated With Mortality in the Intensive Care Unit: A Retrospective Cohort Study.

Jiamei Li, Ruohan Li, Ya Gao, Jingjing Zhang, Yujie Zhao, Xiaoling Zhang, Gang Wang

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jiamei LiDepartment of Critical Care Medicine The Second Affiliated Hospital of Xi'an Jiaotong University Xi'an China.
Ruohan LiDepartment of Critical Care Medicine The Second Affiliated Hospital of Xi'an Jiaotong University Xi'an China.
Ya GaoDepartment of Critical Care Medicine The Second Affiliated Hospital of Xi'an Jiaotong University Xi'an China.
Jingjing ZhangDepartment of Critical Care Medicine The Second Affiliated Hospital of Xi'an Jiaotong University Xi'an China.
Yujie ZhaoDepartment of Critical Care Medicine The Second Affiliated Hospital of Xi'an Jiaotong University Xi'an China.
Xiaoling ZhangDepartment of Critical Care Medicine The Second Affiliated Hospital of Xi'an Jiaotong University Xi'an China.
Gang WangDepartment of Critical Care Medicine The Second Affiliated Hospital of Xi'an Jiaotong University Xi'an China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Disrupted circadian rhythm of blood pressure is commonly observed in patients in the intensive care unit (ICU). This study assessed the association of nocturnal mean arterial pressure rising (NMAPR) with short- and long-term mortality in critically ill adult patients. Methods and Results Adult patients with a complete record of mean arterial pressure monitoring during the first 24 hours of ICU stay in the Multiparameter Intelligent Monitoring in Intensive Care II (MIMIC-II) database were included in this retrospective cohort study. All patients were divided into the non-NMAPR group (≤1) or the NMAPR group (>1), according to the value of mean nighttime divided by daytime mean arterial pressure. The associations of NMAPR with ICU, hospital, 28-day, and 1-year mortality were assessed using multivariable logistic regression or a Cox proportional hazards model. Interaction and subgroup analyses were performed for those patients who had a first Sequential Organ Failure Assessment (SOFA) score of ≥8 or <8. The overall cohort comprised 5185 patients. The patients with NMAPR (n=1865) had higher ICU, hospital, 28-day, and 1-year mortality than the non-NMAPR group (n=3320). After adjusting for covariates, the analysis showed that NMAPR was significantly associated with mortality in the ICU (odds ratio: 1.34; 95% CI, 1.10-1.65), in the hospital (odds ratio: 1.35; 95% CI, 1.12-1.63), at 28 days (hazard ratio: 1.27; 95% CI, 1.10-1.48), and at 1 year (hazard ratio: 1.24; 95% CI, 1.10-1.40). All results of the interaction analysis had no statistical significance, and similar results persisted in the patients with different SOFA scores. Conclusions NMAPR may aid in the early identification of critically ill patients at high risk of ICU, hospital, 28-day, or 1-year mortality.

Indexed as

Arterial PressureCircadian RhythmHospital MortalityIntensive Care UnitsAdolescentAdultBlood Pressure DeterminationCritical IllnessDatabases, FactualEarly DiagnosisFemaleHemodynamic MonitoringHumansMaleMiddle AgedOrgan Dysfunction Scorescircadian rhythmintensive care unitmean arterial pressuremortalityMultiparameter Intelligent Monitoring in Intensive Care II

Identifiers

PMID31566067
PMCPMC6806033

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.