ReviewAIDS research and human retroviruses
Strengths and Limitations of the Veterans Aging Cohort Study Index as a Measure of Physiologic Frailty.
Review in AIDS research and human retroviruses. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed.
- Article
- Association of under-reporting of alcohol use with HIV viral non-suppression and an all-cause mortality risk score among people with HIV on antiretroviral therapy.Journal of acquired immune deficiency syndromes (1999) · 2026Article
- Chronological versus physiological age for 10-year survival estimation: a real-world healthsystem-wide cohort analysis.EBioMedicine · 2026Article
- Frailty and All-Cause Mortality Among People With HIV Engaged in Clinical Care in the United States.Journal of acquired immune deficiency syndromes (1999) · 2026Article
- Article
- Polypharmacy in HIV: Rethinking what counts and why it matters.HIV medicine · 2026Review
- Comparative effectiveness of gabapentin and pregabalin on reduction in alcohol use: A nationwide observational cohort study.medRxiv : the preprint server for health sciences · 2026Article
- The association between long-term opioid therapy and composite infection-related dental outcomes.PloS one · 2026Article
- Anti-GPIIIa antibody and CD4 count identify an autoimmune-enriched phenotype of HIV-associated thrombocytopenia: development and internal validation of a clinical nomogram.Frontiers in immunology · 2026Article
- Depression Improves the Predictive Accuracy of the VACS Index 2.0 for All-Cause Mortality Among Sexual Minority Men Living With HIV in the Multicenter AIDS Cohort Study.Journal of acquired immune deficiency syndromes (1999) · 2025Article
- Association Between Herpes Zoster and Risk of Incident Fragility Fractures in US Veterans: A Matched Cohort Study.Journal of the American Geriatrics Society · 2025Article
- Comparison of 2 electronic health record data extraction methods for laboratory tests used in the Veterans Aging Cohort Study Index.JAMIA open · 2025Article
- Glucagon-like peptide-1 receptor agonists, but not dipeptidyl peptidase-4 inhibitors, reduce alcohol intake.The Journal of clinical investigation · 2025Article
- Assessing intrinsic capacity for person-centred HIV care: a cross-sectional study in ageing populations in Malaysia and Hong Kong.Journal of the International AIDS Society · 2025Article
- Contribution of Potentially Inappropriate Medications to Polypharmacy-Associated Risk of Mortality in Middle-Aged Patients: A National Cohort Study.Journal of general internal medicine · 2024Observational
- Discrimination of the Veterans Aging Cohort Study Index 2.0 for Predicting Cause-specific Mortality Among Persons With HIV in Europe and North America.Open forum infectious diseases · 2024Article
- Article
- Excess mortality in US Veterans during the COVID-19 pandemic: an individual-level cohort study.International journal of epidemiology · 2023Observational
- Review
- Accelerated epigenetic aging in older adults with HIV disease: associations with serostatus, HIV clinical factors, and health literacy.GeroScience · 2023Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
The Veterans Aging Cohort Study Index (VACS Index) is an index comprised of routine clinical laboratory tests that accurately and generalizably predicts all-cause mortality among those living with and without HIV infection. Increasing evidence supports its use as a measure of physiologic frailty among those aging with HIV because of its associations with frailty related outcomes including mortality, hospitalization, fragility fractures, serious falls, pneumonia, cognitive decline, delirium, and functional decline. In this review, we explore the evidence supporting the validity (construct, correlative, and predictive), responsiveness, and feasibility of the VACS Index as an early indicator of physiologic frailty. We also consider its limitations.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.