Evidence map›Paper›PMID 31565536›Full record

ArticleTremor and other hyperkinetic movements (New York, N.Y.)2019

Dorsal GPi/GPe Stimulation Induced Dyskinesia in a Patient with Parkinson's Disease.

Ahmad Elkouzi, Takashi Tsuboi, Matthew R Burns, Robert S Eisinger, Amar Patel, Wissam Deeb

Open access · greenAbstract readCase Reports
In one paragraph

Article in Tremor and other hyperkinetic movements (New York, N.Y.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. A Convergent Pathway for Stimulation-Induced Dyskinesia Following Deep Brain Stimulation.Movement disorders : official journal of the Movement Disorder Society · 2025
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ahmad ElkouziDepartment of Neurology, Southern Illinois University School of Medicine, Springfield, IL, USA.
Takashi TsuboiFixel Institute for Neurological Diseases, Gainesville, FL, USA.
Matthew R BurnsFixel Institute for Neurological Diseases, Gainesville, FL, USA.
Robert S EisingerFixel Institute for Neurological Diseases, Gainesville, FL, USA.
Amar PatelDepartment of Neurology, Yale school of Medicine, Yale University, New Haven, CT, USA.
Wissam DeebFixel Institute for Neurological Diseases, Gainesville, FL, USA.
Southern Illinois University School of Medicine · USYale University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clinical vignette: A 68-year-old man with Parkinson's disease (PD) had bilateral GPi DBS placed for management of his motor fluctuations. He developed stimulation-induced dyskinesia (SID) with left dorsal GPi stimulation. Clinical dilemma: What do we know about SID in PD patients with GPi DBS? What are the potential strategies used to maximize the DBS therapeutic benefit and minimize the side effects of stimulation? Clinical solution: Avoiding the contact implicated in SID and programming more ventral contacts, using lower voltage, frequency and pulse width and programming in bipolar configuration all appear to help minimize the SID and provide appropriate symptomatic motor control. Gap in knowledge: Little is known about SID in patients with PD who had GPi DBS therapy. More studies using volume of tissue activated and diffusion tensor imaging MRI are needed to localize specific tracts in or around the GPi that may be implicated in SID.

Indexed as

Globus PallidusAgedDeep Brain StimulationDyskinesiasHumansMaleParkinson DiseaseDeep Brain Stimulation (DBS)Globus Pallidus Interna (GPi)Parkinson’s Disease (PD)Stimulation Induced Dyskinesia (SID)

Identifiers

PMID31565536
PMCPMC6744811
OpenAlexW2980383557

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.