Evidence map›Paper›PMID 31565530›Full record

ArticleBiomedical optics express2019

Non-invasive cellular-resolution retinal imaging with two-photon excited fluorescence.

Daniel J Wahl, Myeong Jin Ju, Yifan Jian, Marinko V Sarunic

Abstract read
In one paragraph

Article in Biomedical optics express, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Transpupillary in vivo two-photon imaging reveals enhanced surveillance of retinal microglia in diabetic mice.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  2. Frontiers in ophthalmology · 2025
    Review
  3. Article
  4. Article
  5. Noninvasive two-photon optical biopsy of retinal fluorophores.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Daniel J WahlEngineering Science, Simon Fraser University, Burnaby, BC, Canada.
Myeong Jin JuEngineering Science, Simon Fraser University, Burnaby, BC, Canada.
Yifan JianEngineering Science, Simon Fraser University, Burnaby, BC, Canada.
Marinko V SarunicEngineering Science, Simon Fraser University, Burnaby, BC, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two-photon excited fluorescence (TPEF) imaging of the retina is a developing technique that provides non-invasive compound-specific measurements from the retina. In this report, we demonstrate high-resolution TPEF imaging of the mouse retina using sensorless adaptive optics (SAO) and optical coherence tomography (OCT). A single near-infrared light source was used for simultaneous multi-modal imaging with OCT and TPEF. The image-based SAO could be performed using the

Identifiers

PMID31565530
PMCPMC6757458

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.