Evidence map›Paper›PMID 31565524›Full record

ArticleBiomedical optics express2019

Amplification of photoacoustic effect in bimodal polymer particles by self-quenching of indocyanine green.

Maksim D Mokrousov, Marina V Novoselova, Jackie Nolan, Walter Harrington, Polina Rudakovskaya, Daniil N Bratashov, Ekaterina I Galanzha, Juan Pablo Fuenzalida-Werner, Boris P Yakimov, Gleb Nazarikov and 6 more

Abstract read
In one paragraph

Article in Biomedical optics express, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
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  5. Article
  6. iScience · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Maksim D MokrousovSkolkovo Institute of Science and Technology, 3 Nobelya Str, Moscow, 121205, Russia.ORCID https://orcid.org/0000-0002-1688-5144
Marina V NovoselovaSkolkovo Institute of Science and Technology, 3 Nobelya Str, Moscow, 121205, Russia.
Jackie NolanUniversity of Arkansas for Medical Sciences, 4301 W. Markham St. Little Rock, AR 72205, USA.
Walter HarringtonUniversity of Arkansas for Medical Sciences, 4301 W. Markham St. Little Rock, AR 72205, USA.
Polina RudakovskayaSkolkovo Institute of Science and Technology, 3 Nobelya Str, Moscow, 121205, Russia.
Daniil N BratashovSaratov State University, 83 Astrakhanskaya Str, Saratov, 410012, Russia.ORCID https://orcid.org/0000-0002-2096-4478
Ekaterina I GalanzhaUniversity of Arkansas for Medical Sciences, 4301 W. Markham St. Little Rock, AR 72205, USA.
Juan Pablo Fuenzalida-WernerInstitute of Biological and Medical Imaging (IBMI), Helmholtz Zentrum München, Neuherberg, Germany.
Boris P YakimovLomonosov Moscow State University, Leninskie gory 1/2, 119991, Moscow, Russia.
Gleb NazarikovSkolkovo Institute of Science and Technology, 3 Nobelya Str, Moscow, 121205, Russia.
Vladimir P DrachevSkolkovo Institute of Science and Technology, 3 Nobelya Str, Moscow, 121205, Russia.
Evgeny A ShirshinLomonosov Moscow State University, Leninskie gory 1/2, 119991, Moscow, Russia.
Vasilis NtziachristosInstitute of Biological and Medical Imaging (IBMI), Helmholtz Zentrum München, Neuherberg, Germany.
Andre C StielInstitute of Biological and Medical Imaging (IBMI), Helmholtz Zentrum München, Neuherberg, Germany.
Vladimir P ZharovUniversity of Arkansas for Medical Sciences, 4301 W. Markham St. Little Rock, AR 72205, USA.
Dmitry A GorinSkolkovo Institute of Science and Technology, 3 Nobelya Str, Moscow, 121205, Russia.ORCID https://orcid.org/0000-0001-8760-615X

Funding

In vivo real-time detection of circulating melanoma cellsR01CA131164 · NCI · UNIV OF ARKANSAS FOR MED SCIS · PI SUEN, JAMES · 2009 to 2019
$3.1M
NCI NIH HHS R01 CA131164
6 · The paper itself

Abstract

A new type of bimodal contrast agent was made that is based on the self-quenching of indocyanine green (ICG) encapsulated in a biocompatible and biodegradable polymer shell. The increasing of a local ICG concentration that is necessary for the obtaining of self-quenching effect was achieved by freezing-induced loading and layer-by-layer assembly. As a result, an efficient photoacoustic(optoacoustic)/fluorescent contrast agent based on composite indocyanine green/polymer particles was successfully prepared and was characterized by fluorescence and photoacoustic(optoacoustic) tomography

Identifiers

PMID31565524
PMCPMC6757463

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.