ArticleBiomedical optics express2019
Adaptive optics in the mouse eye: wavefront sensing based vs. image-guided aberration correction.
Article in Biomedical optics express, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Evaluation of Shack-Hartmann wavefront sensing artifacts due to reflectivity variations across thick layered samples using the discrete Fourier transform.Biomedical optics express · 2026Article
- Coefficient-metric gradient-based digital wavefront correction for full-field swept-source optical coherence tomography.Biomedical optics express · 2026Article
- Deep reinforcement learning for automatic defocus correction using OCT image intensity.Biomedical optics express · 2025Article
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- Image metric-based multi-observation single-step deep deterministic policy gradient for sensorless adaptive optics.Biomedical optics express · 2024Article
- Adaptive Optical Two-Photon Fluorescence Microscopy Probes Cellular Organization of Ocular Lenses In Vivo.Investigative ophthalmology & visual science · 2023Article
- Article
- Adaptive optical two-photon fluorescence microscopy probes cellular organization of ocular lenses in vivo.bioRxiv : the preprint server for biology · 2023Article
- Adaptive optics scanning laser ophthalmoscopy and optical coherence tomography (AO-SLO-OCT) system forBiomedical optics express · 2023Article
- Wavefront sensor-less adaptive optics using deep reinforcement learning.Biomedical optics express · 2021Article
- Adaptive optics in super-resolution microscopy.Biophysics reports · 2021Article
- Closed-loop wavefront sensing and correction in the mouse brain with computed optical coherence microscopy.Biomedical optics express · 2021Article
- Adaptive optics: principles and applications in ophthalmology.Eye (London, England) · 2021Review
- Measurement of Diurnal Variation in Rod Outer Segment Length In Vivo in Mice With the OCT Optoretinogram.Investigative ophthalmology & visual science · 2020Article
- Adaptive optics two-photon microscopy enables near-diffraction-limited and functional retinal imaging in vivo.Light, science & applications · 2020Article
- Non-invasive cellular-resolution retinal imaging with two-photon excited fluorescence.Biomedical optics express · 2019Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Adaptive Optics (AO) is required to achieve diffraction limited resolution in many real-life imaging applications in biology and medicine. AO is essential to guarantee high fidelity visualization of cellular structures for retinal imaging by correcting ocular aberrations. Aberration correction for mouse retinal imaging by direct wavefront measurement has been demonstrated with great success. However, for mouse eyes, the performance of the wavefront sensor (WFS) based AO can be limited by several factors including non-common path errors, wavefront reconstruction errors, and an ill-defined reference plane. Image-based AO can avoid these issues at the cost of algorithmic execution time. Furthermore, image-based approaches can provide improvements to compactness, accessibility, and even the performance of AO systems. Here, we demonstrate the ability of image-based AO to provide comparable aberration correction and image resolution to the conventional Shack-Hartmann WFS-based AO approach. The residual wavefront error of the mouse eye was monitored during a wavefront sensorless optimization to allow comparison with classical AO. This also allowed us to improve the performance of our AO system for small animal retinal imaging.
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Registered trials
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