ArticleBiomedical optics express2019
Two-photon microperimetry: sensitivity of human photoreceptors to infrared light.
Article in Biomedical optics express, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
21 citing papers in PubMed, 31 citations in OpenAlex.
- Visual Function Loss Through Opacified Media: Comparison Between Single- and Two-Photon Vision.Translational vision science & technology · 2026Article
- [Emerging technology for retinal function testing: two-photon microperimetry].Die Ophthalmologie · 2026Review
- Stiles-Crawford effect in infrared two-photon vision.Biomedical optics express · 2026Article
- Color vision with a two-photon infrared RGB display.Biomedical optics express · 2025Article
- Seeing nonspectral colors with single wavelength stimulation in two-photon vision.Biomedical optics express · 2025Article
- Method for the determination of the luminance of two-photon vision stimuli.Biomedical optics express · 2024Article
- Boosting 2-photon vision with adaptive optics.Journal of vision · 2023Article
- Laser pulse train parameters determine the brightness of a two-photon stimulus.Biomedical optics express · 2023Article
- From mouse to human: Accessing the biochemistry of vision in vivo by two-photon excitation.Progress in retinal and eye research · 2023Review
- Seeing invisible light: 2-photon microperimetry to measure visual function.American journal of ophthalmology case reports · 2022Article
- Femtosecond Er-doped fiber laser source tunable from 872 to 1075 nm for two-photon vision studies in humans.Biomedical optics express · 2022Article
- Two-Photon Vision in Age-Related Macular Degeneration: A Translational Study.Diagnostics (Basel, Switzerland) · 2022Article
- Infrared- and white-light retinal sensitivity in glaucomatous neuropathy.Scientific reports · 2022Article
- In vivo imaging of the human eye using a 2-photon-excited fluorescence scanning laser ophthalmoscope.The Journal of clinical investigation · 2022Article
- Pupillary Light Reflex Induced by Two-Photon Vision.Investigative ophthalmology & visual science · 2021Article
- THE LOSS OF INFRARED LIGHT SENSITIVITY OF PHOTORECEPTOR CELLS MEASURED WITH TWO-PHOTON EXCITATION AS AN INDICATOR OF DIABETIC RETINOPATHY: A Pilot Study.Retina (Philadelphia, Pa.) · 2021Article
- Two-Photon Microperimetry: A Media Opacity-Independent Retinal Function Assay.Translational vision science & technology · 2021Article
- Two-photon microperimetry with picosecond pulses.Biomedical optics express · 2021Article
- Vision with pulsed infrared light is mediated by nonlinear optical processes.Biomedical optics express · 2020Article
- Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
Abstract
Microperimetry is a subjective ophthalmologic test used to assess retinal function at various specific and focal locations of the visual field. Historically, visible light has been described as ranging from 400 to 720 nm. However, we previously demonstrated that infra-red light can initiate visual transduction in rod photoreceptors by a mechanism of two-photon absorption by visual pigments. Here we introduce a newly designed and constructed two-photon microperimeter. We provide for the first time evidence of the presence of a nonlinear process occurring in the human retina based on psychophysical tests using newly developed instrumentation. Since infra-red light penetrates the aged front of the eye better than visible light, it has the potential for improved functional diagnostics in patients with age-related visual disorders.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.