ArticleBiomedical optics express2019
Picometer scale vibrometry in the human middle ear using a surgical microscope based optical coherence tomography and vibrometry system.
Article in Biomedical optics express, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed.
- Differentiating Causes of Post-Surgical Conductive Hearing Loss with Optical Coherence Tomography Vibrometry.Journal of the Association for Research in Otolaryngology : JARO · 2026Article
- Human inner ear fluid imbalance detected by optical coherence tomography correlates with hearing loss.Science translational medicine · 2025Article
- Flexible catheter optical coherence tomography of the porcine middle ear via the Eustachian tube using a 3D-printed reflective objective.Journal of biomedical optics · 2025Article
- Imaging theJournal of biomedical optics · 2025Article
- Optical Coherence Tomography Imaging and Angiography of Skull Base Tumors Presenting as a Middle Ear Mass in Clinic.Diagnostics (Basel, Switzerland) · 2025Article
- Dynamic X-ray Microtomography vs. Laser-Doppler Vibrometry: A Comparative Study.Journal of the Association for Research in Otolaryngology : JARO · 2025Article
- Visualizing motions within the cochlea's organ of Corti and illuminating cochlear mechanics with optical coherence tomography.Hearing research · 2025Review
- Generation of a zebrafish neurofibromatosis model via inducible knockout of nf2a/b.Disease models & mechanisms · 2024Article
- Dynamic X-ray Microtomography vs. Laser-Doppler Vibrometry: A Comparative Study.Research square · 2024Article
- Optical coherence tomography otoscope for imaging of tympanic membrane and middle ear pathology.Journal of biomedical optics · 2024Article
- Generation of a zebrafish neurofibromatosis model via inducible knockout ofbioRxiv : the preprint server for biology · 2024Article
- The Dresden in vivo OCT dataset for automatic middle ear segmentation.Scientific data · 2024Article
- Article
- Electronic frequency shifting enables long, variable working distance optical coherence tomography.Biomedical optics express · 2023Article
- Geometrically accurate real-time volumetric visualization of the middle ear using optical coherence tomography.Biomedical optics express · 2023Article
- Automated classification of otitis media with OCT: augmenting pediatric image datasets with gold-standard animal model data.Biomedical optics express · 2022Article
- Convolutional dictionary learning for blind deconvolution of optical coherence tomography images.Biomedical optics express · 2022Article
- Multimodal Handheld Probe for Characterizing Otitis Media - Integrating Raman Spectroscopy and Optical Coherence Tomography.Frontiers in photonics · 2022Article
- In vivo functional imaging of the human middle ear with a hand-held optical coherence tomography device.Biomedical optics express · 2021Article
- Handheld Briefcase Optical Coherence Tomography with Real-Time Machine Learning Classifier for Middle Ear Infections.Biosensors · 2021Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
We have developed a highly phase stable optical coherence tomography and vibrometry system that attaches directly to the accessory area of a surgical microscope common to both the otology clinic and operating room. Careful attention to minimizing sources of phase noise has enabled a system capable of measuring vibrations of the middle ear with a sensitivity of < 5 pm in an awake human patient. The system is shown to be capable of collecting a wide range of information on the morphology and function of the ear in live subjects, including frequency tuning curves below the hearing threshold, maps of tympanic membrane vibrational modes and thickness, and measures of distortion products due to the nonlinearities in the cochlear amplifier.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.