Evidence map›Paper›PMID 31565155›Full record

ArticleOxidative medicine and cellular longevity2019

Effect of Zinc on the Oxidative Stress Biomarkers in the Brain of Nickel-Treated Mice.

Jurgita Šulinskienė, Rasa Bernotienė, Dalė Baranauskienė, Rima Naginienė, Inga Stanevičienė, Artūras Kašauskas, Leonid Ivanov

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 27 citations in OpenAlex.

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  10. NEUROTOXICITY OF METAL MIXTURES.Advances in neurotoxicology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jurgita ŠulinskienėNeuroscience Institute, Lithuanian University of Health Sciences, Kaunas LT-50161, Lithuania.ORCID https://orcid.org/0000-0001-6348-1460
Rasa BernotienėNeuroscience Institute, Lithuanian University of Health Sciences, Kaunas LT-50161, Lithuania.
Dalė BaranauskienėNeuroscience Institute, Lithuanian University of Health Sciences, Kaunas LT-50161, Lithuania.
Rima NaginienėNeuroscience Institute, Lithuanian University of Health Sciences, Kaunas LT-50161, Lithuania.ORCID https://orcid.org/0000-0001-5770-2618
Inga StanevičienėFaculty of Medicine, Medical Academy, Lithuanian University of Health Sciences, Kaunas LT-50161, Lithuania.
Artūras KašauskasFaculty of Medicine, Medical Academy, Lithuanian University of Health Sciences, Kaunas LT-50161, Lithuania.ORCID https://orcid.org/0000-0002-9601-5877
Leonid IvanovFaculty of Medicine, Medical Academy, Lithuanian University of Health Sciences, Kaunas LT-50161, Lithuania.
Lithuanian University of Health Sciences · LT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The overexposure to nickel due to the extensive use of it in modern technology remains a major public health concern. The mechanisms of pathological effects of this metal remain elusive. The present study was devoted to evaluate the effect of nickel on the oxidative state of the brain cells of mice and to assess whether zinc as redox state modulator could efficiently protect cells against nickel's neurotoxicity. As oxidative stress biomarkers in the present study, we have measured the concentrations of reduced glutathione, metallothioneins, and malondialdehyde and the activity of the enzyme

Indexed as

AnimalsBiomarkersBrainMiceNickelOxidative StressZincBiomarkersNickelZinc

Identifiers

PMID31565155
PMCPMC6745131
OpenAlexW2971893678

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.