ReviewNeural plasticity2019
Emerging Roles of Synapse Organizers in the Regulation of Critical Periods.
Review in Neural plasticity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 30 citations in OpenAlex.
- Firemaster 550 differentially alters gene expression underlying synaptic function in amygdala of prairie voles after gestational or lactational exposure.Neurotoxicology · 2026Article
- Investigating hierarchical critical periods in human neurodevelopment.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Review
- Human thalamocortical structural connectivity develops in line with a hierarchical axis of cortical plasticity.Nature neuroscience · 2025Article
- The Balance in the Head: How Developmental Factors Explain Relationships Between Brain Asymmetries and Mental Diseases.Brain sciences · 2025Review
- A sensorimotor-association axis of thalamocortical connection development.bioRxiv : the preprint server for biology · 2024Article
- Visual cortex repetitive transcranial magnetic stimulation (rTMS) reversing neurodevelopmental impairments in adolescents with major psychiatric disorders (MPDs): A cross-species translational study.CNS neuroscience & therapeutics · 2024Article
- Neurexin-2: An inhibitory neurexin that restricts excitatory synapse formation in the hippocampus.Science advances · 2023Article
- Article
- Engineered synaptic tools reveal localized cAMP signaling in synapse assembly.The Journal of cell biology · 2022Article
- Non-Cell-Autonomous Factors Implicated in Parvalbumin Interneuron Maturation and Critical Periods.Frontiers in neural circuits · 2022Review
- Understanding Language Reorganization With Neuroimaging: How Language Adapts to Different Focal Lesions and Insights Into Clinical Applications.Frontiers in human neuroscience · 2022Review
- Molecular self-avoidance in synaptic neurexin complexes.Science advances · 2021Article
- Expression of early growth responsive gene-1 in the visual cortex of monocular form deprivation amblyopic kittens.BMC ophthalmology · 2021Article
- SALM4 negatively regulates NMDA receptor function and fear memory consolidation.Communications biology · 2021Article
- Article
- Synaptic recognition molecules in development and disease.Current topics in developmental biology · 2021Article
- Brain region-dependent alterations in polysialic acid immunoreactivity across the estrous cycle in mice.Hormones and behavior · 2020Article
- Deorphanizing FAM19A proteins as pan-neurexin ligands with an unusual biosynthetic binding mechanism.The Journal of cell biology · 2020Article
- Clmp Regulates AMPA and Kainate Receptor Responses in the Neonatal Hippocampal CA3 and Kainate Seizure Susceptibility in Mice.Frontiers in synaptic neuroscience · 2020Article
- Stability in the Face of Change: Lifelong Experience-Dependent Plasticity in the Sensory Cortex.Frontiers in cellular neuroscience · 2020Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Experience remodels cortical connectivity during developmental windows called critical periods. Experience-dependent regulation of synaptic strength during these periods establishes circuit functions that are stabilized as critical period plasticity wanes. These processes have been extensively studied in the developing visual cortex, where critical period opening and closure are orchestrated by the assembly, maturation, and strengthening of distinct synapse types. The synaptic specificity of these processes points towards the involvement of distinct molecular pathways. Attractive candidates are pre- and postsynaptic transmembrane proteins that form adhesive complexes across the synaptic cleft. These synapse-organizing proteins control synapse development and maintenance and modulate structural and functional properties of synapses. Recent evidence suggests that they have pivotal roles in the onset and closure of the critical period for vision. In this review, we describe roles of synapse-organizing adhesion molecules in the regulation of visual critical period plasticity and we discuss the potential they offer to restore circuit functions in amblyopia and other neurodevelopmental disorders.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.