ArticleClinical, cosmetic and investigational dentistry2019
The role of salivary sIgA as protection for dental caries activity in Indonesian children.
Article in Clinical, cosmetic and investigational dentistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.
- Exploring potential salivary biomarkers for dental caries: a systematic review.Medicina oral, patologia oral y cirugia bucal · 2025Pooled it
- Association of salivary proteins with dental caries in children with mixed dentition: a systematic review.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2025Pooled it
- Trial
- Analysis of Saliva Composition: Parathyroid Hormone-Related Protein, Total Protein, and Secretory Immunoglobulin A (sIgA) in Rattus norvegicus with Stunted Growth.European journal of dentistry · 2023Article
- Impact of breastfeeding and other early-life factors on the development of the oral microbiome.Frontiers in microbiology · 2023Review
- Differentially Expressed Salivary Proteins in Dental Caries Patients.BioMed research international · 2021Article
- Evaluation of possible biomarkers for caries risk in children 6 to 12 years of age.Journal of oral microbiology · 2021Article
- Association between salivary s-IgA concentration and dental caries: A systematic review and meta-analysis.Bioscience reports · 2020Article
- Role of natural salivary defenses in the maintenance of healthy oral microbiota in children and adolescents.Journal of family medicine and primary care · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim of this study is to asses the relationship between the level of sIgA and dental caries experience in healthy children who are 6- to 9-years-old from Indonesia. The case-control study is conducted to determine the protective role of salivary secretory immunoglobulin A (sIgA) levels in the stimulated whole saliva of dental caries-active and caries-free children.
methodsThis research was done by stimulating the whole saliva which had been collected from 6- to 9-years-old children with the index
resultsThe total salivary concentration of sIgA was statistically significantly higher in the low caries-active children group than in the caries-active children group.
conclusionThe total salivary concentration of sIgA was statistically and significantly higher in the low caries-active children group than caries-active children Group. There is a negative correlation between sIgA level and dental caries activity of 6 to 9-years-old children.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.