Evidence map›Paper›PMID 31564945›Full record

ArticleClinical, cosmetic and investigational dermatology2019

Emollient formulations containing antiseptics reduce effectively the level of

Fabrizio Spada, Tanya M Barnes, Kerryn A Greive

Abstract read
In one paragraph

Article in Clinical, cosmetic and investigational dermatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Fabrizio SpadaResearch & Development, Ego Pharmaceuticals, Braeside, Victoria, Australia.ORCID 0000-0002-3324-6301
Tanya M BarnesResearch & Development, Ego Pharmaceuticals, Braeside, Victoria, Australia.
Kerryn A GreiveResearch & Development, Ego Pharmaceuticals, Braeside, Victoria, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIncreased skin colonization by

methodsThe antimicrobial activity of topical products including a bath oil, cream, and wash combining antiseptics and emollients (A+E) was compared to products containing emollients only. The preference of patients with AE for A+E cream or emollient only cream to relieve symptoms of itching, erythema, and inflammation when applied three times daily for 10 days is evaluated. Repeat insult patch testing of the products is also conducted.

resultsA significant reduction in microbial counts was found following use of A+E bath oil (4.09±0.32 vs 6.20±0.24 log

conclusionThe bath oil, cream, and wash containing antiseptics and emollients decrease the level of bacteria on the skin, including

Indexed as

antimicrobialantisepticatopic dermatitisatopic eczemabenzalkonium chlorideemollientStaphylococcus aureustriclosan

Identifiers

PMID31564945
PMCPMC6735249

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.