Evidence map›Paper›PMID 31564924›Full record

ArticleInfection and drug resistance2019

Emergence of novel methicillin-resistant

Abiola Senok, Ali M Somily, Rania Nassar, Ghada Garaween, Garwin Kim Sing, Elke Müller, Annett Reissig, Darius Gawlik, Ralf Ehricht, Stefan Monecke

Abstract read
In one paragraph

Article in Infection and drug resistance, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Antibacterial Potential ofFoods (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Emergence of livestock-associated MRSA in the Egyptian Nile Delta that carry the exfoliative toxin gene etA: a case for enhanced surveillance.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Article
  8. Article
  9. Molecular epidemiology of methicillin-resistantFrontiers in microbiology · 2025
    Review
  10. Characterisation of PVL-PositiveAntibiotics (Basel, Switzerland) · 2024
    Article
  11. Article
  12. Article
  13. Clonal Flux and Spread ofMicroorganisms · 2023
    Article
  14. Article
  15. Community-Acquired Methicillin-ResistantDiagnostics (Basel, Switzerland) · 2023
    Article
  16. Article
  17. A Sequalae of Lineage Divergence inDiagnostics (Basel, Switzerland) · 2023
    Article
  18. Article
  19. Characterisation of Methicillin-ResistantAntibiotics (Basel, Switzerland) · 2023
    Article
  20. Comparative genomic analysis of antibiotic resistance and virulence genes inFrontiers in cellular and infection microbiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Abiola SenokDepartment of Basic Medical Sciences, College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, United Arab Emirates.ORCID 0000-0001-6382-198X
Ali M SomilyDepartment of Pathology and Laboratory Medicine, College of Medicine, King Khalid University Hospital and King Saud University, Riyadh, Saudi Arabia.
Rania NassarDepartment of Basic Medical Sciences, College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, United Arab Emirates.
Ghada GaraweenDepartment of Microbiology and Immunology, College of Medicine, Alfaisal University, Riyadh, Saudi Arabia.
Garwin Kim SingDepartment of Microbiology and Immunology, College of Medicine, Alfaisal University, Riyadh, Saudi Arabia.
Elke MüllerInfectoGnostics Research Campus Jena, Jena, Germany.
Annett ReissigInfectoGnostics Research Campus Jena, Jena, Germany.
Darius GawlikPTC - Phage Technology Center GmbH, Bönen, Germany.
Ralf EhrichtInfectoGnostics Research Campus Jena, Jena, Germany.
Stefan MoneckeInfectoGnostics Research Campus Jena, Jena, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThere is a need for continuous surveillance of methicillin-resistant

methodsMRSA isolates associated with invasive clinical infection, which were identified in 2017 at the microbiology laboratory, King Khalid University Hospital (KKUH) in Riyadh, Saudi Arabia, were studied. The molecular characterization of isolates was carried out using StaphyType DNA microarray (Alere Technologies GmbH/Abbott, Jena, Germany).

resultsThe 125 MRSA isolates studied belonged to 18 clonal complexes (CC) which were distributed into 32 strain assignments. The predominant CC were CC5 (n=30), CC6 (n=17), CC80 (n=13), CC22 (n=12), CC361 (n=12). The findings demonstrated the first identification of CC152, CC361 and CC1153 MRSA as well as ST5-MRSA-[I+fus], "Geraldine Clone", CC6-MRSA-IV (PVL+) and CC88-MRSA-V (PVL+), WA MRSA-117 in Saudi Arabia. Four novel variants were identified: CC5-MRSA-[VI+fus+tirS], CC22-MRSA-[V/VT+fus](PVL+), CC152-MRSA-[V+fus](PVL+) and CC361-MRSA-[VT+fus]. Fifty-four isolates (n/N=54/125; 43.2%) including the novel strains carried the Q6GD50 SCC

conclusionThe findings demonstrate an expanding MRSA repertoire in our setting including emergence of previously unreported clonal complexes and novel strains. The high carriage of

Indexed as

clonal complexDNA microarrayfusidic acidpanton-valentine leukocidin

Identifiers

PMID31564924
PMCPMC6731981

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.