ArticleNeuropsychiatric disease and treatment2019
Affective theory of mind in Parkinson's disease: the effect of cognitive performance.
Article in Neuropsychiatric disease and treatment, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
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Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Social cognition in Parkinson's disease: a comprehensive systematic review and integrative conceptual framework.Frontiers in aging neuroscience · 2026Pooled it
- Assessing social cognition in patients with schizophrenia and healthy controls using the reading the mind in the eyes test (RMET): a systematic review and meta-regression.Psychological medicine · 2024Pooled it
- Domain-driven verbal and non-verbal dissociations in cognition and social cognition in Parkinson's disease.Frontiers in psychology · 2026Article
- Psychiatric neurosurgery and the Theory of Mind network: ethics in the suffering, refractory patient.Dementia & neuropsychologia · 2026Review
- Dispositional and situational empathy in Parkinson's disease and their relationship with cognition.Frontiers in psychology · 2025Article
- Reading the mind in the eyes in patients with idiopathic REM sleep behavior disorder.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Article
- Social Cognition and Mild Cognitive Impairment in Mid-Stage Parkinson's Disease.Behavioral sciences (Basel, Switzerland) · 2024Article
- A 20-Year Systematic Review of the 'Reading the Mind in the Eyes' Test across Neurodegenerative Conditions.Brain sciences · 2023Review
- Social and non-social working memory in neurodegeneration.Neurobiology of disease · 2023Article
- Social Cognition in Parkinson's Disease: A Case-Control Study.Movement disorders clinical practice · 2023Article
- Distribution of α-Synuclein Aggregation in the Peripheral Tissues.Neurochemical research · 2022Review
- Mild cognitive impairment in patients with Parkinson's disease: An updated mini-review and future outlook.Frontiers in aging neuroscience · 2022Review
- Cognitive dysfunction in young subjects with periodontal disease.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021Article
- Well-Being, Depression, and Anxiety following Oncoplastic Breast Conserving Surgery versus Modified Radical Mastectomy Followed by Late Breast Reconstruction.International journal of environmental research and public health · 2021Article
- Current advances in metabolomic studies on non-motor psychiatric manifestations of Parkinson's disease (Review).Experimental and therapeutic medicine · 2021Review
- Parkinson's Disease in Romania: A Scoping Review.Brain sciences · 2021Article
- Social and Neurocognitive Deficits in Remitted Patients with Schizophrenia, Schizoaffective and Bipolar Disorder.Healthcare (Basel, Switzerland) · 2021Article
- Social Cognition in Patients with Early-Onset Parkinson's Disease.Parkinson's disease · 2021Article
- Social Inferences as Mediators of Wellbeing in Depression.Neuropsychiatric disease and treatment · 2021Article
- Levodopa-Carbidopa Intestinal Gel Infusion Therapy Discontinuation: A Ten-Year Retrospective Analysis of 204 Treated Patients.Neuropsychiatric disease and treatment · 2020Article
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Authors and funding
6 authors.
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No grant is acknowledged in the PubMed record.
Abstract
purposeAmong other non-motor symptoms, theory of mind (ToM), the ability to recognize, understand and infer others' mental states, beliefs, intents and wishes, has been shown to deteriorate during the course of Parkinson's disease (PD). It has been speculated that ToM impairments could be related to cognitive deficits in PD. However, the current state of literature suggests that there is heterogeneity regarding the involvement of cognitive functioning in the relationship of PD and ToM. The study aimed to measure affective ToM abilities and cognitive performance in a sample of PD patients, to explore the link between affective ToM abilities and cognitive status, and to examine the impact of PD on affective ToM through the mediator effect of cognitive performance. PATIENTS AND
methodsSixty-five patients diagnosed with idiopathic PD and 51 healthy controls matched for age, gender and educational level completed a visual affective ToM task (Reading the Mind in the Eyes - RMET), cognitive performance was evaluated with Montreal Cognitive Assessment, and psychiatric symptoms were measured with BPRS-E (Brief Psychiatric Rating Scale).
resultsAffective ToM abilities were preserved in early PD patients, declining as the disease progressed. Deficits in cognitive functioning predicted deficiencies in affective ToM. Although attention (AT), executive functions (EF) and visuospatial abilities (VSA) together mediated the relationship between PD and affective ToM, only VSA impairment had a specific negative impact on affective ToM. Moreover, 41% of the total effect of attention and executive functions on affective ToM was mediated by visuospatial skills.
conclusionCognitive performance may have an impact on the relationship between PD and affective ToM through the involvement of VSA. The influence of AT and EF in this relationship appears to be also exerted by PD patients' VSA.
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